Monday, June 10, 2013
Medical Sciences Building (MSB), University of Toronto
1 King's College Circle
Collaborative Program In Neuroscience (CPIN) Research Day
9:30 Pre-event Career Workshop (MSB 2172)
11:00 Meet with Workshop speakers (Stone Lobby)
11:30 Registration and poster set-up (Stone Lobby)
12:00 Opening remarks
12:15 poster presentation grouping, judges, and Rules of Poster Presentation Awards and Student’s Choice Awards
Pick-up Lunch
12:30 - 16:00 CPIN Poster Presentation and evaluation (Stone Lobby)
16:00 CPIN Group Photo
(Outside of MSB by J.J.R. MacLeod Auditorium)
Raymond and Beverly Sackler Distinguished Lecture (Macleod Auditorium)
16:30 Welcome remarks
16:45 Brian Kobilka (Stanford University, U.S.A.),
Structural Insights into the Dynamic Process of G-protein-coupled Receptor Activation
17:45 CPIN Poster presentation awards announcement
Please click here for information on our sponsors
Tuesday, June 11, 2013
International Symposium on Structural Neurobiology
Organized by Oliver Ernst, Canada Excellence Research Chair in Structural Neurobiology, University of Toronto
Room B-150 (1 floor below ground level)
Pharmacy Building, University of Toronto
144 College St.
9:00 - 10:30 Session 1
G-Protein Coupled Receptors (GPCRs)
Chair: Brian Kobilka (Stanford University, U.S.A.),
9:00 Opening remarks
9:10 Scott Prosser (University of Toronto, Canada), GPCR Dynamics - Understanding the Role of Ligands on GPCR Activation by Using 19F NMR
9:35 Oliver Ernst (University of Toronto, Canada), Structural Insights into First Steps of Seeing
10:00 Dwayne Miller (University of Hamburg, Germany/University of Toronto, Canada), Rhodopsin Family of Sensory Proteins Breaks Speed Records – New Questions on the Role of Quantum Effects in Biology
10:35 - 11:00 Coffee Break
11:00 Tom Sakmar (Rockefeller University, New York, U.S.A.), Probing Receptor Activation with Genetically-Encoded Unnatural Amino Acids
11:35 John J. Irwin & Brian K. Shoichet (University of California, San Francisco, U.S.A./University of Toronto, Canada), Structure-Based and Chemoinformatics Discovery of GPCR Ligands and Pharmacology
12:05 - 14:00 Lunch and Poster Session
14:00 - 15:35 Session 2
Transporters and Ion channels
Chair: Reinhart Reithmeier (University of Toronto, Canada)
14:05 Da-Neng Wang (New York University School of Medicine, New York, U.S.A.), Structure and Mechanism of a Bacterial INDY Homolog — A Sodium-dependent Carboxylate Transporter Involved in Fatty Acid Synthesis and Obesity
14:40 Ernst Bamberg (Max Planck Institute of Biophysics, Frankfurt, Germany), Light-gated ion channels and pumps in optogenetics
15:15 Emil Pai (University of Toronto, Canada), Analysis of the Bacterial Mg2+ Channel CorA in the Presence and Absence of Divalent Ions
15:40 - 16:00 Coffee Break
16:00 - 17:10 Session 3
Approaches to Drug Discovery
Chair: Ruth Ross (University of Toronto, Canada)
16:05 Ron Dror (D.E. Shaw Research, New York, U.S.A.), How Drugs Bind and Control their Targets: Characterizing GPCR Signaling Through Atomic-level Simulation
16:40 Andrew Doré, Heptares Therapeutics Ltd (Welwyn Garden City, UK), StaR’s® and Structures: Enabling GPCR Drug Discovery
17:15 Closing remarks - end of the scientific meeting