Recent Advances and Uses of PROTACs in Drug Discovery

Structural Genomics Consortium
Tuesday, March 6, 2018 - 9:00am to 1:00pm
Barclay Room, Intercontinental Toronto Yorkville Hotel, 220 Bloor Street West

Mini-Symposium: Recent Advances and Uses of PROTACs in Drug Discovery

The Structural Genomics Consortium (SGC) in Toronto invites you to attend our symposium on Recent Advances and Uses of PROTACs in Drug Discovery. Join us to hear the latest about this emerging drug discovery strategy from leaders in the field.

Registration deadline is March 2nd at 12pm EST. Registration is free but required. Space is limited.

Organizing Committee: Cheryl Arrowsmith, Arij Al Chawaf, Matthieu Schapira, Rebecca Clare, Santha Santhakumar.

For enquiries, please contact Arij Al Chawaf:



09:00 - 09:40am

Dr. Alessio Ciulli
Professor of Chemical Structural Biology, Principal
Investigator at the School of Life Sciences
University of Dundee, Dundee, UK
Title: Targeted protein degradation: How PROTACs work

9:45 - 10:25am

Dr. Stacey-Lynn Paiva
Postdoctoral Research Associate, Crews Laboratory, MCDB
Yale University, New Haven CT, USA
Title: PROTAC-mediated Protein Degradation: A New Therapeutic Modality

10:30 - 11:00am


11:00 - 11:40am

Dr. Danette Daniels
Group Leader, Functional Proteomics
Promega, Madison, WI, USA
Title: Characterizing kinetics and functional mechanisms of BET family PROTACs

11:45am - 12:10pm

Dr. Rajesh Chopra
Director, Cancer Research UK Cancer Therapeutics Unit,
Head, Division of Cancer Therapeutics
The Institute of Cancer Research, London, UK
Title: TBA


Roundtable discussion (Chair: Tim Willson, UNC-Chapel Hill)
Panel: Drs Alessi Ciulli, Stacey-Lynn Paiva, Danette Daniels, Rajesh Chopra, Stefan Knapp (Göethe Frankfurt University)