Japan-Toronto Morphogenesis Symposium

Peter Gilgan Centre for Research and Learning
Monday, July 16, 2018 - 12:30pm to Tuesday, July 17, 2018 - 6:30pm
PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids

Japan-Toronto Morphogenesis Symposium

Robert B. Salter Auditorium

Peter Gilgan Centre for Research and Learning

The Hospital for Sick Children



Monday, July 16, 2018

12:30-12:45     REGISTRATION – Second floor lobby

12:45              Opening Remarks – Sevan Hopyan

12:50                Introduction to 3D Morphologic – Shigeru Kondo


Session I – 1:00-3:00 PM

Chair: TBD

1:00-1:30      Shizue Ohsawa – Kyoto University

        3D morphogenesis of adult appendages from the Folded Epithelial Sheets in Drosophila

1:30-2:00      Shigeru Kondo – Osaka University

        The reversed ORIGAMI mechanism that determines the 3D shape of the exoskeleton

2:00-2:20      Dorothea Godt, U of T

                     Regulation of actomyosin activity by Protein Kinase C delta during collective cell migration

2:20-2:40      Ulrich Tepass, U of T

      Integration of polarity, adhesion, cytoskeletal dynamics and vesicle trafficking during epithelial cell ingression

2:40-3:00      Rodrigo Fernandez-Gonzalez, U of T

        Oxidative stress orchestrates cell polarity during embryonic wound repair


3:00-3:30      COFFEE BREAK


Session II – 3:30-5:10 PM

Chair: TBD

3:30-4:00      Takeo Matsumoto – Nagoya University

        Biomechanical approaches toward elucidation of mechanical environment in Xenopus laevis embryos

4:00-4:20      Yu Sun, U of T

        Tools for measuring physical properties in vivo

4:20-4:50      Guy Tanentzapf, University of British Columbia

                     Analysis of Cell-ECM Adhesion During Morphogenesis & Tissue Maintenance in Flies & Mice

4:50-5:10      Rudolf Winklbauer, U of T

                     Cell-cell attachment mechanisms and the range of adhesion strengths


Tuesday, July 17, 2018

Session III – 9:00-10:20 AM

Chair: TBD

9:00-9:15      Toru Kawanishi – University of Tokyo

        Coordinated tissue elongation in the zebrafish posterior body

9:15-9:30      Yue Tong – University of Tokyo

        Rotational cell migration: a new logic behind 3D somite morphogenesis

9:30-9:50      Sevan Hopyan, U of T

                     Mesenchymal cell rearrangements that shape tissue in the mouse embryo

9:50-10:20    Naoto Ueno – National Institute for Basic Biology

        Calcium dynamics and tissue mechanics of vertebrate neural tube closure


10:20-10:50  COFFEE BREAK


Session IV – 10:50 AM-12:20 PM

Chair: TBD

10:50-11:20  Kenji Matsuno. – Osaka University

        Cell chirality drives left-right asymmetric morphogenesis

11:20-11:40  Julie Brill, U of T

                     Regulation of cell adhesion by the lipid phosphatase Sac I

11:40-12:00  Julie Lefebvre, U of T

                     Molecular and dynamic cellular determinants of dendrite morphogenesis

12:00-12:20  Ran Kafri, U of T

                     Size sensing mechanisms in animal cells


12:20-1:30   LUNCH – PGCRL Gallery


Session V – 1:30-3:30 PM

Chair: TBD

1:30-2:00      Masakazu Akiyama – Hokkaido University

                     A mathematical model of collective cell migration based on cell polarity

2:00-2:30      Matthias Merkel, Syracuse University

        Physical multi-scale approaches to study the mechanics of 3D biological tissues

2:30-3:00      Yasuhiro Inoue – Kyoto University

        Computational simulation on multiple cell dynamics in tissue deformation

3:00-3:30      Jennifer Schwarz, Syracuse University

                     Buckling without bending: A new paradigm in morphogenesis


3:30-4:00      COFFEE BREAK


Session VI – 4:00-5:30 PM

Chair: TBD

4:00-4:20      Sid Goyal, U of T

                     Can Single-Cell Transcriptional Profiling shed light on morphogenesis?

4:20-4:40      Brian Ciruna, U of T

                     Understanding the causes of idiopathic scoliosis: a twisted ‘tail’ of cilia and CSF flow defect

4:40-5:00      Penney Gilbert, U of T

                     3D culture models of human skeletal muscle to uncover new biology

5:00-5:30      Hisashi Haga – Hokkaido University

                     Collective movement and 3D morphogenesis of epithelial cells responding to viscoelastic substrates


5:30-6:30     FAREWELL RECEPTION (Cash Bar)

                    PGCRL Gallery