Previous Seminars

Tuesday, February 27, 2018 - 4:00pm

Phosphoinositide signalling and cancer: Novel functions for INPP4B in hematopoiesis and leukemogenesis John F. Woolley Ph.D. Department of Pharmacology & Toxicology, University of Toronto Tuesday, February 27, 2018 - 4:00pm Host: Leonardo Salmena, Department of Pharmacology & Toxicology, University of Toronto MSB 2170 Pharmacology and Toxicology Seminar Departmental Seminar Poster available: Woolley Poster Feb 27.pdf

Wednesday, February 28, 2018 - 1:00pm

Dish Microglia: Towards Synthetic Models of Human Neuro-Immune Interactions Dr. Julien Muffat SickKids Research Institute Wednesday, February 28, 2018 - 1:00pm Host: Dr. Leah Cowen MSB 4171 Department of Molecular Genetics Faculty Recruitment Seminar Poster available: Muffat Poster.pdf

Wednesday, February 28, 2018 - 4:00pm

Accessing ‘Cryptic’ Metabolites Through Genetic Manipulation of Streptomyces Isolates Martin Daniel-Ivad PhD Student Wednesday, February 28, 2018 - 4:00pm Supervisor: Dr. Justin Nodwell, Committee: Drs. Alan Davidson & Roman Melnyk MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Hedgehog pathway regulates ciliogenesis Tara Akhshi PhD Student Wednesday, February 28, 2018 - 4:00pm Supervisor: Dr. Bill Trimble, Committee: ? MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Health research in an age of borderless science Dr. Alan Bernstein President, CIFAR Wednesday, February 28, 2018 - 4:00pm Mt. Sinai Hospital, 18th Floor Auditorium Lunenfeld-Tanenbaum Seminar Series Special Seminar Poster available: 09142_P(8.5x11)_20180110_FINAL.PDF

Integrative drug classification based on big pharmacogenomic data Benjamin Haibe-Kains Principal Investigator, Princess Margaret Cancer Centre Wednesday, February 28, 2018 - 4:00pm Host: TorBUG CCBR Red Room TorBUG Invited Speaker Seminar

Clusters of cis-regulatory elements as epigenomic features predictive of drug response Ali Madani Tonekaboni Graduate Student, Haibe-Kains and Lupien labs Wednesday, February 28, 2018 - 4:00pm Host: TorBUG CCBR Red Room TorBUG Trainee Speaker

Thursday, March 1, 2018 - 12:00pm

Molecular Simulations of Intrinsically Disordered Proteins Prof. Sarah Rauscher Department of Chemical and Physical Sciences, University of Toronto, Mississauga Thursday, March 1, 2018 - 12:00pm Host: Dr. Anton Zilman McLennan Physical Laboratories, Room MP606 BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: Rauscher_March1.pdf

CFTR correction using advanced gene editing tools Dr. Jim Hu Thursday, March 1, 2018 - 12:00pm Hospital for Sick Children, 555 University Avenue, Room 1527, Hill Wing Cystic Fibrosis Seminar

Thursday, March 1, 2018 - 4:00pm

Friday, March 2, 2018 - 10:00am

Friday, March 2, 2018 - 1:00pm

Expanding the Applications of Mitochondrial Targeted Delivery Peptides Eric Lei Friday, March 2, 2018 - 1:00pm Supervisor: Dr. Shana Kelley MSB 4171 Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.Eric_.Lei_.pdf

Friday, March 2, 2018 - 2:00pm

Monday, March 5, 2018 - 11:00am

Monday, March 5, 2018 - 4:00pm

Endothelial Anomalies in Vascular Tumors and Vascular Malformations Joyce Bischoff, PhD Professor, Surgery, Harvard Medical School, Principal Investigator, Vascular Biology Program and Surgery, Boston Children's Hospital Monday, March 5, 2018 - 4:00pm Host: Jason Fish, PhD, jason.fish@utoronto.ca MSB 2170 Laboratory Medicine and Pathobiology Seminar Invited Speaker Seminar Poster available: Poster JBischoff.pdf

Wednesday, March 7, 2018 - 12:00pm

Resolution of Topoisomerase 2 DNA-protein crosslinks Dr. Scott Williams Senior Investigator and Deputy Chief Genome Integrity and Structural Biology Laboratory National Institutes of Health, National Institutes of Environmental Health Sciences Wednesday, March 7, 2018 - 12:00pm Host: Dr. Daniel Durocher Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 Lunenfeld-Tanenbaum Seminar Series Invited Speaker Seminar Poster available: Scott Williams Poster.pdf

Wednesday, March 7, 2018 - 4:00pm

Thursday, March 8, 2018 - 11:00am

Neuronal transcriptome profiling identifies a conserved ubiquitin ligase complex involved in serotonergic neuromodulation in C. elegans John Calarco, PhD Assistant Professor, Department of Cell & Systems Biology | Associate, Medicine by Design | University of Toronto Thursday, March 8, 2018 - 11:00am Host: Peter J. Roy, PhD, Canada Research Chair in Chemical Genetics, Professor/Vice Chair, Department of Molecular Genetics, The Donnelly Centre, Department of Pharmacology & Toxicology, University of Toronto CCBR Red Room Donnelly Seminar Series Departmental Seminar Poster available: John Calarco 08 Mar 2018 Donnelly poster.pdf

Thursday, March 8, 2018 - 12:00pm

Cancer Nanomedicine: The challenge of targeting nanoparticles into solid tumors Prof. Warren Chan Prof. Warren Chan Institute of Biomaterials & Biomedical Engineering (IBBME), Donnelly Centre for Cellular and Biomolecular Research (CCBR) Departments of Materials Science and Engineering, Chemical Engineering, Chemistry, University of Toronto Thursday, March 8, 2018 - 12:00pm Host: Dr. Anton Zilman McLennan Physical Laboratories, Room MP606 BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: WChan_March8.pdf

“Genetic Disorders of Protein Coats: The Case of AP-4 Defects in Hereditary Spastic Paraplegia” Juan Bonifacino National Institutes of Health Thursday, March 8, 2018 - 12:00pm ENG102 (ENG is located at the southeast corner of Gould and Church Sts.) Molecular Science Seminar Series (Ryerson)

Thursday, March 8, 2018 - 4:00pm

Selective targeting of kinase catalytic and non-catalytic function Professor Stefan Knapp Professor of Pharmaceutical Chemistry University of Oxford & Johann Wolfgang Goethe-University Frankfurt, Germany Thursday, March 8, 2018 - 4:00pm Host: Dr. Cheryl Arrowsmith PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Poster available: PM CC Seminar Notice_Professor Stefan Knapp.pdf

Friday, March 9, 2018 - 1:30pm

Touched by a macrophage: macrophage-tumor cell communication in tumor progression. Dianne Cox, PhD Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University. Friday, March 9, 2018 - 1:30pm PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Cox.pdf

Friday, March 9, 2018 - 2:00pm

Friday, March 9, 2018 - 4:00pm

FMRP and RNA phase separation in activity-dependent translation Julie Forman-Kay Sickkids Research Hospital, University of Toronto, Department of Biochemistry Friday, March 9, 2018 - 4:00pm Host: Toronto RNA Club CCBR Red Room Toronto RNA Club Special Seminar Poster available: Toronto RNA Club March 2018.pdf

Monday, March 12, 2018 - 11:00am

Monday, March 12, 2018 - 4:00pm

Changing Landscape of Bladder Cancer Management: The Impact of Genomics and Immunotherapy George J. Netto MD Professor and Chair of Pathology, Robert and Ruth Anderson Endowed Chair in Pathology, The University of Alabama,Birmingham Monday, March 12, 2018 - 4:00pm Host: George Yousef, MD PhD FRCPC MSc MBBCh, YousefG@smh.ca MSB 2170 Laboratory Medicine and Pathobiology Seminar Invited Speaker Seminar Poster available: Poster GNetto.pdf

Tuesday, March 13, 2018 - 4:00pm

Bipolar Disorder as a Vascular Disease: Research and Clinical Implications Benjamin Goldstein M.D. Ph.D. Professor, Psychiatry and Pharmacology, University of Toronto, Faculty of Medicine Director, Centre for Youth Bipolar Disorder Senior Scientist, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre Tuesday, March 13, 2018 - 4:00pm Host: Dr. Walter Swardfager Ph.D MSB 2170 Pharmacology and Toxicology Seminar Departmental Seminar Poster available: Goldstein Poster March 13.pdf

Wednesday, March 14, 2018 - 9:00am

The Effect of Natural Variation on Perturbed Phenotypes in Caenorhabditis elegans Victoria Vu PhD Candidate Wednesday, March 14, 2018 - 9:00am Supervisor: Dr. Andrew Fraser CCBR Red Room Department of Molecular Genetics PhD Oral Seminar Poster available: Vu Poster.pdf

Wednesday, March 14, 2018 - 12:00pm

Synaptic connectomes of model nervous systems: their collection and utility Dr. Ian Meinertzhagen Department of Psychology and Neuroscience, Dalhousie University; Senior Fellow, Janelia Research Campus of HHMI Wednesday, March 14, 2018 - 12:00pm Host: Dr. Mei Zhen Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 Lunenfeld-Tanenbaum Seminar Series Invited Speaker Seminar Poster available: Ian Meinertzhagen Poster.pdf

Wednesday, March 14, 2018 - 4:00pm

Thursday, March 15, 2018 - 4:00pm

Friday, March 16, 2018 - 1:30pm

Lineage, cancer superclasses and the upside-down world of RB, MYC and YAP. Rod Bremner, PhD Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital. Friday, March 16, 2018 - 1:30pm PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Bremner.pdf

Friday, March 16, 2018 - 2:00pm

Monday, March 19, 2018 - 11:00am

Genome organization of dengue and Zika viruses Yue Wan, PhD Senior Research Scientist, Genome Institute of Singapore |Adjunct Assistant Professor | Department of Biochemistry, National University of Singapore | A*STAR Investigator, Society in Science- Branco Weiss | Fellow | EMBO Young Investigator Monday, March 19, 2018 - 11:00am Host: Benjamin (Ben) Blencowe, PhD | Professor, The Donnelly Centre, Department of Molecular Genetics, Biography: Yue Wan received her B.Sc in Cell Biology and Biochemistry from the University of California, San Diego. She obtained her Ph.D in Cancer Biology from Stanford University, California, USA, under the mentorship of Howard Y. Chang. During her PhD CCBR Red Room Blencowe Lab Seminar Invited Speaker Seminar Poster available: yue wan.compressed.pdf

Neutrophil activation phenotype in response to specific oral commensal and oral pathogenic bacteria. Morvarid Oveisi M.Sc. Candidate, Glogauer lab, Faculty of Dentistry, University of Toronto Monday, March 19, 2018 - 11:00am Supervisor: Dr. Michael Glogauer Fitzgerald Building, Room #237 Matrix Dynamics Group Seminar Research Group Seminar

Tuesday, March 20, 2018 - 10:30am

Regulatory Interactions Within the Respiratory Chain Peter Brzezinski, PhD Professor, Department of Biochemistry & Biophysics, Stockholm University, Sweden Tuesday, March 20, 2018 - 10:30am Host: Dr. John Rubinstein PGCRL Event Rooms 3A/3B (03.9310, 3rd Floor) Molecular Medicine Seminar Series Special Seminar Poster available: Brzezinski_SeminarPoster_20Mar2018.pdf

Tuesday, March 20, 2018 - 11:00am

Functional heterogeneity of DNA repair capacity Dr. Jay Hesselberth, PhD Associate Professor, Biochemistry and Molecular Genetics -- University of Colorado School of Medicine Tuesday, March 20, 2018 - 11:00am Host: Dr. Michael Hoffman, PhD PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Special Seminar Special Seminar Poster available: Seminar Notice for Posting- Dr. Jay Hesselberth.pdf

Tuesday, March 20, 2018 - 4:00pm

Application of CRISPR/Cas9 technology for functional genomics screens in mammalian cells Dr. Michael Aregger Dr. Jason Moffat Lab, Donnelly Centre Tuesday, March 20, 2018 - 4:00pm Host: Donnelly Centre TechTalks CCBR Red Room Donnelly CCBR Seminar Poster available: 20180320-Aregger-TechTalk.pdf

Cannabinoid therapeutics - mixed messages Ruth Ross Ph.D. Professor and Chair, Pharmacology & Toxicology Senior Scientist, Campbell Family Mental Health Research Institute, CAMH Faculty of Medicine Tuesday, March 20, 2018 - 4:00pm Host: Leonardo Salmena Ph.D MSB 2170 Pharmacology and Toxicology Seminar Poster available: Ross Poster Mar 20.pdf

Wednesday, March 21, 2018 - 2:00pm

Topoisomerase II and gliomas: Transcriptional regulation and personalized targeting. Dr. Adam Sonabend Director, Translational Brain Tumor Laboratory, Northwestern University Wednesday, March 21, 2018 - 2:00pm Hospital for Sick Children, 555 University Avenue, Room 1246 Black Wing BTRC Seminar Series Invited Speaker Seminar Poster available: Sonabend Poster.pdf

Wednesday, March 21, 2018 - 4:00pm

Thursday, March 22, 2018 - 9:00am

Integrins are key mediators of cell state and tumour heterogeneity Allison Nixon PhD Candidate Thursday, March 22, 2018 - 9:00am Supervisor: Dr. Jason Moffat MSB 4171 Department of Molecular Genetics PhD Oral Seminar Poster available: Nixon Poster.pdf

Thursday, March 22, 2018 - 12:00pm

Exploiting stochastic fluctuations to understand cellular processes and infer biochemical kinetics Dr. Andreas Hilfinger Department of Physics, U of T Thursday, March 22, 2018 - 12:00pm Host: Dr. Anton Zilman McLennan Physical Laboratories, Room MP606 BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: AHilfinger_March22.pdf

Anti-Prion Systems in Yeast and inositol polyphosphates Dr. Reed B. Wickner National Institutes of Health Thursday, March 22, 2018 - 12:00pm Host: Dr. Marc Meneghini CCBR Red Room Department of Molecular Genetics Invited Speaker Seminar Poster available: Wickner Poster.pdf

Thursday, March 22, 2018 - 1:30pm

Viral-like mechanisms of intercellular trafficking of RNA in the nervous system Dr. Jason Shepherd Department of Neurobiology and Anatomy University of Utah, School of Medicine Thursday, March 22, 2018 - 1:30pm Host: Dr. Paul Frankland, and Dr. Tod Thiele Hospital for Sick Children, 555 University Avenue, Room 1246 Black Wing Neurosciences and Mental Health Program Seminars Departmental Seminar Poster available: Shepherd.pdf

Thursday, March 22, 2018 - 4:00pm

Coordinated Regulation of Metabolic Transporters and Tumour Cell Migration/Invasion by Hypoxia-Induced Carbonic Anhydrase IX Dr. Shoukat Dedhar University of British Columbia Thursday, March 22, 2018 - 4:00pm Host: Dr. Jason Moffat CCBR Red Room Department of Molecular Genetics Invited Speaker Seminar Poster available: Dedhar Poster.pdf

Friday, March 23, 2018 - 10:00am

H3K4 methylation dependent and independent chromatin regulation by JHD2 and SET1 in budding yeast Kwan Yin Lee PhD Candidate Friday, March 23, 2018 - 10:00am Supervisor: Dr. Marc Meneghini MSB 2172 Department of Molecular Genetics PhD Oral Seminar Poster available: Lee Poster.pdf