Previous Seminars

Friday, May 4, 2018 - 11:00am

Versatile tools towards real-time single-molecule biology Rosalie Driessen Lumicks Inc. Friday, May 4, 2018 - 11:00am Host: Walid Houry MaRS 1522 Special Seminar Poster available: LUMICKS_Toronto University.pdf

Monday, May 7, 2018 - 11:00am

Monday, May 7, 2018 - 4:00pm

BRCA1 function and mammary differentiation control Emmanuel Farber Distinguished Visiting Lectureship, David M. Livingston, M.D. Emil Frei Professor of Genetics and Medicine, Harvard Medical School, Deputy Director, Dana-Farber/Harvard Cancer Center Monday, May 7, 2018 - 4:00pm Host: K. Mekhail, PhD & R. Hakem, PhD, karim.mekhail@utoronto.ca & rhakem@uhnres.utoronto.ca Medical Sciences Building, Room 2170 Laboratory Medicine and Pathobiology Seminar Departmental Seminar Poster available: 2018 EFarber Lectureship.pdf

Tuesday, May 8, 2018 - 4:00pm

The endocannabinoid system and addiction-relevant phenotypes Dr. Isabelle Boileau Head, Addiction Imaging Research Group & Clinical Research Scientist, Campbell Family Mental Health Research Institute, CAMH Tuesday, May 8, 2018 - 4:00pm Host: Dr. Rachel Tyndale MSB 2170 Pharmacology and Toxicology Seminar Invited Speaker Seminar Poster available: Boileau Poster May 8.pdf

Wednesday, May 9, 2018 - 12:00pm

The 5th element: Genomic consequences of embedded ribonucleotides and other stories’ Dr. Andrew Jackson MRC Institute of Genetics and Molecular Medicine, the University of Edinburgh Wednesday, May 9, 2018 - 12:00pm Host: Dr. Daniel Durocher Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 Lunenfeld-Tanenbaum Seminar Series Invited Speaker Seminar Poster available: Andrew Jackson Poster.pdf

Wednesday, May 9, 2018 - 2:00pm

Structural and mechanistic characterization of the core mammalian Hippo tumor suppressor pathway Shawn Xiong Wednesday, May 9, 2018 - 2:00pm Supervisor: Dr. Frank Sicheri MSB 2173 Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.Shawn_.Xiong_.pdf

Wednesday, May 9, 2018 - 4:00pm

Thursday, May 10, 2018 - 10:30am

A novel feedback loop connects oncogenic signaling to miRNA metabolism Dr. Ilka Heinemann Assistant Professor of Biochemistry, Western University Thursday, May 10, 2018 - 10:30am Host: Dr. Julie Claycomb MaRS, Room 1622 Department of Molecular Genetics Invited Speaker Seminar Poster available: Heinemann Poster.pdf

Thursday, May 10, 2018 - 12:00pm

Thursday, May 10, 2018 - 4:00pm

Friday, May 11, 2018 - 1:30pm

A signaling gradient hierarchy regulates pattern formation during cell repair. William M. Bement, PhD Laboratory of Cell and Molecular Biology, University of Wisconsin - Madison Friday, May 11, 2018 - 1:30pm PG CRL Rm 3a, 3rd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Bement.pdf

Friday, May 11, 2018 - 2:00pm

Monday, May 14, 2018 - 11:00am

Monday, May 14, 2018 - 12:00pm

Novel biological functions of the Crohn’s disease risk factor NOD2  Dr. Dave Prescott University of Toronto Monday, May 14, 2018 - 12:00pm Supervisor: Stephen Girardin CCBR Red Room Donnelly Centre Postdoc/Research Associate Seminar series Poster available: Dave Prescott.pdf

Monday, May 14, 2018 - 4:00pm

Single Cell Genomics Reveals Distinct Macrophage Populations in the Human Liver Sonya MacParland, PhD Assistant Scientist, Toronto General Hospital Research Institute, Assistant Professor, University of Toronto, Departments of LMP and Immunology Monday, May 14, 2018 - 4:00pm Host: Jason Fish, PhD, jason.fish@utoronto.ca MSB 2170 Laboratory Medicine and Pathobiology Seminar Invited Speaker Seminar Poster available: Poster SMacParland.pdf

Tuesday, May 15, 2018 - 12:00pm

Optogenetics for intracellular codebreaking: How ERK activity is interpreted to control gene expression and cell fate Jared Toettcher, PhD Princeton University Tuesday, May 15, 2018 - 12:00pm Host: Penney Gilbert Red Room, Donnelly Centre, 160 College Street Medicine by Design Global Speaker Series Special Seminar Co-sponsor: Ontario Institute for Regenerative Medicine Poster available: GlobalSpeakerSeries_Poster_Jared Toettcher.pdf

Tuesday, May 15, 2018 - 4:00pm

Drugging Protein-Protein Interactions: Two Case Studies From The Ontario Institute for Cancer Research Dr. Rima Al-awar Director and Senior Principal Investigator, Drug Discovery Program, OICR Tuesday, May 15, 2018 - 4:00pm Host: Dr. Leonardo Salmena MSB 2170 Pharmacology and Toxicology Seminar Invited Speaker Seminar Poster available: Al-awar Poster May 1.pdf

Wednesday, May 16, 2018 - 12:00pm

Maternal and Fetal Forms of a Microsatellite in the HMOX1 Promoter Are Associated with Different Preeclampsia Subtypes Dr. Miira Klemetti Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital Wednesday, May 16, 2018 - 12:00pm Host: Dr. Isabella Caniggia Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 Lunenfeld-Tanenbaum Seminar Series Poster available: Miira Klemetti Poster.pdf

Wednesday, May 16, 2018 - 3:00pm

“Structural basis of phosphoinositide and Rab GTPase signalling and their roles in human disease. John Burke, PhD Department of Biochemistry and Microbiology, University of Victoria Wednesday, May 16, 2018 - 3:00pm PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Burke.pdf

Rapid Determination of Tumour Pathology With Picosecond InfraRed Laser Mass Spectrometry: Identifying Medulloblastoma Subgroup Affiliations With only 10 Seconds of Sampling and Analysis Dr. Arash Zarrine-Afsar Department of Surgery & Department of Medical Biophysics, University of Toronto Wednesday, May 16, 2018 - 3:00pm Hospital for Sick Children, 555 University Avenue, Room 1246 Black Wing Program in Cell Biology Seminar Series  Special Seminar

Wednesday, May 16, 2018 - 4:00pm

Friday, May 18, 2018 - 12:00pm

Growth coordination mechanisms during Drosophila development Pierre Leopold Institut Valrose Biologie, Univ. Nice Sophia Antipolis, Genetics and Developmental Biology Unit Friday, May 18, 2018 - 12:00pm Host: Marla Sokolowski Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology

Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity Matthew T. Weirauch, PhD University of Cincinnati Center for Autoimmune Genomics and Etiology | Cincinnati Children's Hospital Medical Center | Cincinnati, OhioT Friday, May 18, 2018 - 12:00pm Host: Timothy R. Hughes, Professor, The Donnelly Centre, Department of Molecular Genetics, University of Toronto CCBR Red Room Hughes Lab Seminar Poster available: Weirauch_poster_May_2018.pdf

Friday, May 18, 2018 - 1:30pm

Inter-membrane lipid transport and regulation by OSBPs. Neale Ridgway, PhD Department of Biochemistry and Molecular Biology, Dalhousie University. Friday, May 18, 2018 - 1:30pm PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Ridgway.pdf

Monday, May 21, 2018 - 4:00pm

Probing neurodegeneration with genome-wide perturbations and 3D histology Dr. Adriano Aguzzi Director, Institute of Neuropathology, University of Zurich Monday, May 21, 2018 - 4:00pm Host: Dr. Igor Stagljar CCBR Red Room Department of Biochemistry George Connell Lecture Poster available: Connell 2019_Adriano Aguzzi.pdf

Tuesday, May 22, 2018 - 10:30am

Multiscale spectroscopies for understanding GPCR mediated cell signalling Anthony Watts Biomembrane Structure Unit, Department of Biochemistry, University of Oxford Tuesday, May 22, 2018 - 10:30am Host: Dr. Oliver Ernst CCBR Red Room BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: AnthonyWatts_May 22_2018-1.pdf

Wednesday, May 23, 2018 - 3:00pm

Retrotransposons as agents of somatic diversity, disease and aging Dr. Stephen Helfand Department of Molecular Biology, Cell Biology and Biochemistry, Brown University Wednesday, May 23, 2018 - 3:00pm Host: Dr. Joe Culotti Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 Lunenfeld-Tanenbaum Seminar Series Invited Speaker Seminar Poster available: Stephen Helfand Poster.pdf

Thursday, May 24, 2018 - 10:10am

Functional and Structural Characterization of human Rvb1 and Rvb2 and Screening for Inhibitors of their ATPase Activity Nardin Nano Thursday, May 24, 2018 - 10:10am Supervisor: Dr. Walid Houry MSB 2173 Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.Nardin.Nano_.pdf

Thursday, May 24, 2018 - 11:00am

Future Anti-Cancer Targets: Put the Horses Before the Carts Tak Wah Mak, PhD, OC, OOnt, FRS, FRSC University Professor, Departments of Immunology and Medical Biophysics, University of Toronto | Director, The Campbell Family Institute for Breast Cancer Research | Senior Scientist, Princess Margaret Cancer Centre Thursday, May 24, 2018 - 11:00am Host: Igor Stagljar, PhD | Professor, The Donnelly Centre, Department of Biochemistry CCBR Red Room Donnelly Seminar Series Invited Speaker Seminar Poster available: Tak W Mak poster 24 May 2018.compressed.pdf

Thursday, May 24, 2018 - 12:00pm

Thursday, May 24, 2018 - 3:00pm

Transcriptional stress networks underlying phenotypic plasticity in the tumor microenvironment Ruth Scherz-Shouval, PhD Assistant Professor, Weizmann Institute of Science Thursday, May 24, 2018 - 3:00pm Host: Mikko Taipale, PhD, Canada Research Chair in Functional Proteomics and Proteostasis, Assistant Professor, The Donnelly Centre, Department of Molecular Genetics CCBR Red Room Invited Speaker Seminar Poster available: Ruth Scherz-Shouval poster.pdf

Thursday, May 24, 2018 - 4:00pm

Thursday, May 24, 2018 - 4:30pm

STI1/HOP (Hsp70-Hsp90 organizing protein) regulation of cellular resilience and protein misfolding Marco A. M. Prado Molecular Medicine, Robarts Research Institute, The University of Western Ontario Thursday, May 24, 2018 - 4:30pm Host: Dr. Walid Houry CCBR Red Room BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: MarcoPrado_May 24_2018.pdf

Friday, May 25, 2018 - 12:00pm

Improving the identification of reproducible and reliable phenotypic endpoints through natural history studies of rodent models of monogenic neurodevelopmental disorders Rodney C. Samaco, PhD Assistant Professor,Department of Molecular and Human Genetics, Baylor College of Medicine (BCM) Friday, May 25, 2018 - 12:00pm Host: Monica Justice, PhD PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Genetics & Genome Biology Program Invited Speaker Seminar Co-sponsor: Centre for Brain & Mental Health Poster available: GGB_CBMH_SAMACO_2018May25.pdf

Friday, May 25, 2018 - 1:30pm

Mitochondrial quality control, autophagy and Parkinson’s disease. Richard J. Youle, PhD Biochemistry Section, Surgical Neurology, NINDS/NIH Friday, May 25, 2018 - 1:30pm PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Youle.pdf

Friday, May 25, 2018 - 2:00pm

Friday, May 25, 2018 - 2:30pm

“PDX Finder: Building Global Standards and Partnerships for PDX models” Terry Meehan, PhD European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI), Cambridge, UK Friday, May 25, 2018 - 2:30pm Host: Benjamin Haibe-Kains, PhD MaRS- TMDT R# 4-204, 4th floor Special Seminar Poster available: Terry Meehan_PM Special Seminar_ May 25, 2018.pdf

Monday, May 28, 2018 - 12:00pm

Exploring the frontiers of genomic medicine in congenital muscular dystrophy Dr. Dwi U. Kemaladewi SickKids Research Institute Monday, May 28, 2018 - 12:00pm CCBR Red Room Donnelly Centre Postdoc/Research Associate Seminar series Poster available: Dwi Kemaladewi.pdf

Monday, May 28, 2018 - 1:00pm

PI4P and the biogenesis of regulated secretory granules Julie Brill, PhD Cell Biology, SickKids Research Institute, Department of Molecular Genetics, University of Toronto Monday, May 28, 2018 - 1:00pm Host: Dr. Julie Forman-Kay PGCRL Event Rooms 3A/3B (03.9310, 3rd Floor) Molecular Medicine Seminar Series Invited Speaker Seminar Poster available: MM Seminar - Dr. Brill May 28.pdf

Wednesday, May 30, 2018 - 3:00pm

Looking at neurological disorders from different perspectives Dr. Lee Rubin Professor, Stem Cell and Regenerative Biology, Harvard University, Director of Translational Medicine, Harvard Stem Cell Institute Wednesday, May 30, 2018 - 3:00pm Host: DSCB Trainees PG CRL Auditorium, 686 Bay St., SickKids Developmental and Stem Cell Biology Invited Speaker Seminar Poster available: Lee Rubin Seminar Announcement.pdf

Thursday, May 31, 2018 - 11:00am

Cellular Aging, Chromatin and Genome Replication Antonio (Toni) Bedalov, MD, PhD Attending Physician, University of Washington (UW) Medical Center | Associate Member, Fred Hutch Clinical Research Division Fred Hutchinson Cancer Research Center Associate Professor, Department of Chemistry, University of Washington, Seattle, WA Thursday, May 31, 2018 - 11:00am Host: Igor Stagljar, PhD CCBR Red Room Donnelly Seminar Series Invited Speaker Seminar Poster available: Antonio Bedalov 31 May 2018 donnelly poster.pdf

Thursday, May 31, 2018 - 12:00pm

Thursday, May 31, 2018 - 4:00pm

Regulation of adult muscle stem cell quiescence by Notch signaling Dr. Meryem Baghdadi Institut Pasteur Thursday, May 31, 2018 - 4:00pm Host: Dr. Tae-Hee Kim PG CRL Rm 3.9320, 3rd Fl. Multi-Media Room, 686 Bay St., Sickkids Developmental and Stem Cell Biology Special Seminar

Human Cancer Epigenetics: From Knowledge to Applications Dr. Manel Esteller Director, Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute (IDIBELL) Spain Thursday, May 31, 2018 - 4:00pm Host: Dr. Daniel De Carvalho, Senior Scientist PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Poster available: Seminar Notice for Posting_Esteller.pdf

Friday, June 1, 2018 - 1:00pm

Next Generation Approaches for Understanding Physical and Genetic Networks Albi Celaj PhD Candidate, Department of Molecular Genetics Friday, June 1, 2018 - 1:00pm Supervisor: Dr. Frederick P. Roth MSB 4171 PhD Exam Seminar Poster available: Celaj Poster.pdf

Thursday, June 7, 2018 - 11:00am

Biased agonism in receptor tyrosine kinase (RTK) signalling Dr. Mark Lemmon, Professor of Pharmacology Yale University School of Medicine Thursday, June 7, 2018 - 11:00am Host: Dr. Sachdev Sidhu CCBR Red Room Poster available: Lemmon poster.pdf

Thursday, June 7, 2018 - 12:00pm

Thursday, June 7, 2018 - 1:00pm

A Genome-Scale Analysis of Alternative Splicing Regulation by Splicing Factors in C. elegans June Tan PhD Candidate Thursday, June 7, 2018 - 1:00pm Supervisor: Dr. Andrew Fraser MSB 4279 Department of Molecular Genetics PhD Exam Seminar Poster available: Tan Poster.pdf

Thursday, June 7, 2018 - 4:00pm