Archived Biochemistry Seminars

Wednesday, December 6, 2017 - 4:00pm

Characterization of Type I-F Anti-CRISPRs: Mechanism and Function Eric Lu MSc Student Wednesday, December 6, 2017 - 4:00pm Supervisor: Dr. Alan Davidson: Committee: Drs. Trevor Moraes, Karen Maxwell MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, November 29, 2017 - 4:00pm

Assessing membrane contact sites during maturation of intracellular Salmonella: implications for cholesterol trafficking Glenn Walpole PhD Student Wednesday, November 29, 2017 - 4:00pm Supervisor: Dr. Sergio Grinstein & Dr. John Brumell, Committee: Dr. Peter Kim & Dr. Mathieu Lemaire MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Systematic identification of gemcitabine sensitivity and resistance mechanisms in pancreatic ductal adenocarcinoma Tajinder Ubhi PhD Student Wednesday, November 29, 2017 - 4:00pm Supervisor: Dr. Grant Brown, Committee members: Dr. Daniel Durocher & Dr. Stephane Angers MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Peptide-based inhibitors of bacterial small multidrug resistance efflux pumps Chloe Mitchell MSc Student Wednesday, November 29, 2017 - 4:00pm Supervisor: Dr. Charlie Deber, Committee: Dr. Roman Melnyk and Dr. Reinhart Reithmeier MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, November 22, 2017 - 4:00pm

Idenitification of new Hippo pathway regulators using a genome wide CRISPR screen Sabrina Sen PhD Student Wednesday, November 22, 2017 - 4:00pm Supervisor: Dr. Liliana Attisano, Committee members Dr. Stephane Angers, Dr. Andras Kapus and Dr. Igor Stagljar. MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

New Players in the Selective Autophagy of Peroxisomes Nicholas Demers MSc Student Wednesday, November 22, 2017 - 4:00pm Supervisor: Dr. Peter Kim, Committee members Dr. John Brumell and Dr. Daniela Rotin MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

investigation of the contribution of Hif-1alpha NODD to the interaction with VHL Wenguang He MSc Student Wednesday, November 22, 2017 - 4:00pm Supervisor: Michael Ohh & Jeff Lee, Committee members: Liliana Attisano & Mitsuhiko Ikura MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, November 15, 2017 - 4:00pm

Unraveling the Critical Role of Src and ND2 in the Up-regulation of NMDA Receptors Shuo-Chih Yen MSc Student Wednesday, November 15, 2017 - 4:00pm Supervisor: Dr. Julie Forman-Kay, Committee members: Dr. Jason Maynes, Dr. Mitsu Ikura and Dr. Frank Sicheri MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Discovery of natural products against Clostridium difficile protein toxin Simoun Icho MSc Student Wednesday, November 15, 2017 - 4:00pm Supervisor: Dr. Roman Melnyk, Committee: Dr. Jean-Philippe Julien and Dr. Justin Nodwell MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Determining the Fibrillization Mechanism of Serum Amyloid A Asal Nady MSc Student Wednesday, November 15, 2017 - 4:00pm Supervisor: Dr. Simon Sharpe, Committee: Dr. Joel Watts and Dr. Jean-Phillipe Julien MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, November 8, 2017 - 4:00pm

Utilizing high-throughput screening and drug repurposing to rescue TTC7A mutant phenotype associated with VEOIBD Sasha Jardine MSc Student Wednesday, November 8, 2017 - 4:00pm Supervisor: Dr. Aleixo Muise, Committee: Dr. Roman Melnyk and Dr. James Dowling MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

No topic submitted Stephanie Tan MSc Student Wednesday, November 8, 2017 - 4:00pm Supervisor: Dr. Justin Nodwell MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Determining the Structure of the VPS33B-VPS16B Membrane Tethering Complex Jia Yuan (Richard) Liu PhD Student Wednesday, November 8, 2017 - 4:00pm Supervisor: Dr. Walter Kahr, Committee Dr. John Rubinstein and Dr. Peter Kim MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, November 8, 2017 - 9:00am

Clostridium difficile Toxins: Entry and Uptake Zhifen Zhang Wednesday, November 8, 2017 - 9:00am Supervisor: Dr. Roman Melnyk MSB 4171 Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.Zhifen.Zhang_.pdf

Wednesday, November 1, 2017 - 4:00pm

Elucidating the role of PGAM5 in Mitophagy Sudeshna Nag MSc Student Wednesday, November 1, 2017 - 4:00pm Supervisor: Dr. Angus McQuibban MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Role of the lyase AlgL in Pseudomonas aeruginosa alginate biosynthesis Andreea Gheorghita MSc Student Wednesday, November 1, 2017 - 4:00pm Supervisor: Dr. Lynne Howell MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Monday, October 30, 2017 - 2:00pm

HIV-1 Vpu Oligomerization in Membrane Mimetics David Davidson Monday, October 30, 2017 - 2:00pm Supervisor: Dr. Simon Sharpe CCBR Red Room Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.D.Davidson.pdf

Wednesday, October 25, 2017 - 4:00pm

Substrate processing and mechanochemical coupling of the 26S proteasome – a fine-tuned molecular machine Andy Martin HHMI, UC Berkeley, Department of Molecular & Cell Biology Wednesday, October 25, 2017 - 4:00pm Host: Julianne Burçoğlu (Enenkel Lab) MSB 2172 Department of Biochemistry George Connell Lecture Poster available: Andreas Martin Poster.pdf

Wednesday, October 18, 2017 - 4:00pm

Molecular Characterization of Antibodies Against Malaria Transmission Blocking Antigen Pfs25² Brandon McLeod PhD Student Wednesday, October 18, 2017 - 4:00pm Supervisor: Dr. Jean-Philippe Julien, Committee members: Dr. Kevin Kain, and Dr. Trevor Moraes MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

No topic submitted Brian Tsang MSc Student Wednesday, October 18, 2017 - 4:00pm Supervisor: Dr. Julie Forman-Kay MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Investigating non-canonical Hedgehog signalling in cell migration Cheryl Chan MSc Student Wednesday, October 18, 2017 - 4:00pm Supervisor: Dr. William Trimble, Committee: Dr. Chi-Chung Hui, Dr. Sergio Grinstein MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, October 11, 2017 - 4:00pm

Exploring the Role of Anaplastic Lymphoma Kinase and Leukocyte Tyrosine Kinase within the Human Central Nervous System Adam Sivitilli MSc Student Wednesday, October 11, 2017 - 4:00pm Supervisor: Dr. Liliana Attisano, Committee Members: Dr. Jeffrey Wrana, Dr. Carol Schuurmans & Dr. Michael Ohh MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Charaterization of the substrate specificity of HDAC3 Yi Zhang MSc Student Wednesday, October 11, 2017 - 4:00pm Supervisor: Dr. Gil Prive, Committee: Eric Campos and James Rini. MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, October 4, 2017 - 4:00pm

Polarity regulated Hippo Pathway signaling in lung development and disease Dr. Bob Varelas Boston University Wednesday, October 4, 2017 - 4:00pm Host: Liliana Attisano MSB 2172 Department of Biochemistry George Connell Lecture Poster available: Varelas Poster.pdf

Tuesday, October 3, 2017 - 1:30pm

Identification and characterization of novel upstream regulators of the Hippo signalling pathway Emad Heidaryasrash Tuesday, October 3, 2017 - 1:30pm Supervisor: Dr. Liliana Attisano CCBR Red Room Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.Emad_.H.pdf

Wednesday, September 20, 2017 - 4:00pm

The Molecular Machinery of Protein Degradation - Structural Studies ex situ and in situ Prof. Wolfgang Baumeister Director, Max Planck Institute of Biochemistry, Martinsried, Germany Wednesday, September 20, 2017 - 4:00pm Host: Julianne Burçoǧlu (Cordula Enenkel Lab) MSB 2172 Department of Biochemistry George Connell Lecture Poster available: Baumeister Poster.pdf

Monday, September 18, 2017 - 9:30am

The Molecular Action of Actinorhodin, an Antibiotic Produced by Streptomyces coelicolor Stefanie Mak Monday, September 18, 2017 - 9:30am Supervisor: Dr. Justin Nodwell CCBR Red Room Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.S.Mak_.pdf

Monday, September 11, 2017 - 2:00pm

Structural and Functional Characterization of RAF Allosteric Regulation" Neroshan Thevakumaran Monday, September 11, 2017 - 2:00pm Supervisor: Dr. Frank Sicheri CCBR Red Room Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.Nero_.T.pdf

Wednesday, August 16, 2017 - 1:00pm

Role of Peroxisome Quality Control Factors in Pexophagy and Peroxisome Biogenesis Disorders Kelsey Law Wednesday, August 16, 2017 - 1:00pm Supervisor: Dr. Peter Kim MSB 4171 Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.K.Law_.pdf

Thursday, August 3, 2017 - 11:00am

Structural and mechanistic insight into bacterial amyloid secretion and assembly Dr. Steve Matthews Professor of Chemical and Structural Biology, Imperial College London Thursday, August 3, 2017 - 11:00am Host: Dr. Trevor Moraes CCBR Red Room Department of Biochemistry Seminar Special Seminar Poster available: BCH Special Seminar Steve Matthews.pdf

Wednesday, June 28, 2017 - 4:00pm

The Mechanochemical Regulation of Taz Expression Maria Miranda Graduate Student Wednesday, June 28, 2017 - 4:00pm Supervisor: Andras Kapus and Craig Simmons, Committee members: Katalin Szaszi, Amira Klip, and Boris Hinz MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, June 14, 2017 - 4:00pm

Characterization of Slam-dependent surface lipoprotein translocation Yogesh Hooda PhD Student Wednesday, June 14, 2017 - 4:00pm Supervisor: Dr. Trevor Moraes, Committee: Drs. Roman Melnyk & Will Navarre MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Mitochondrial targeting of small molecule ligands using releasable peptide vectors Eric Lei PhD Student Wednesday, June 14, 2017 - 4:00pm Supervisor: Shana Kelley, Committee Members : Roman Melnyk, Justin Nodwell MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Friday, June 9, 2017 - 9:00am

INVESTIGATING THE CELLULAR EFFECTS OF MITOCHONDRIAL DNA DAMAGE USING TARGETED CHEMICAL PROBES Simon Wisnovsky Friday, June 9, 2017 - 9:00am Supervisor: Dr. Shana Kelley Pharmacy Building Room 850 Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.S.Wisnovsky.pdf

Wednesday, June 7, 2017 - 4:00pm

Phospho-dependent regulation of the core Hippo Pathway by MOB1 protein Shawn Xiong PhD Student Wednesday, June 7, 2017 - 4:00pm Supervisor: Frank Sicheri, Committee: Helen McNeil and Avi Chakrabartty MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Structural insights into protein translocation by a AAA+ unfoldase Zev Ripstein PhD Student Wednesday, June 7, 2017 - 4:00pm Supervisor: John Rubinstein, Co-supervisor: Lewis Kay MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, May 31, 2017 - 4:00pm

Investigating the Balance Between SPOP and ERG in Prostate Cancer Darren Yong PhD Student Wednesday, May 31, 2017 - 4:00pm Supervisor: Gil Prive, Committee: Frank Sicheri and Trevor Moraes MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

PIPKH: a Pseudo-kinase involved in phosphoinositide metabolism Yanbo Yang PhD Student Wednesday, May 31, 2017 - 4:00pm Supervisor: Greg Fairn, Committee members: Julie Brill and William Trimble MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, May 24, 2017 - 4:00pm

Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif Noah Manczyk PhD Student Wednesday, May 24, 2017 - 4:00pm Supervisor: Dr. Frank Sicheri, Committee: Dr. Stephane Angers, Dr. Grant Brown PG CRL Auditorium, 686 Bay St., SickKids Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Biosynthesis of the Pel polysaccharide in Pseudomonas aeruginosa proceeds via the formation of a multipurpose membrane complex Greg Whitfield PhD Student Wednesday, May 24, 2017 - 4:00pm Supervisor: Dr. Lynne Howell, Committee Members: Drs. Trevor Moraes & Frank Sicheri PG CRL Auditorium, 686 Bay St., SickKids Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, May 17, 2017 - 4:00pm

The RavA-ViaA System Interacts with and Modulates the Activity of the Fumarate Reductase Respiratory Complex Vaibhav Bhandari PhD Student Wednesday, May 17, 2017 - 4:00pm Supervisor: Dr. Walid Houry Committee: Dr. Trevor Moraes and Dr. Roman Melnyk PG CRL Auditorium, 686 Bay St., SickKids Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Deciphering the regulatory role of Septin9 N-terminus in mammalian septin polymerization Forooz Soroor PhD Student Wednesday, May 17, 2017 - 4:00pm Supervisor: Dr. William Trimble, Committee: Dr. Julie Brill and Dr. John Rubinstein PG CRL Auditorium, 686 Bay St., SickKids Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, May 10, 2017 - 4:00pm

Unearthing New Natural Products from the Soil Martin Daniel-Ivad PhD Student Wednesday, May 10, 2017 - 4:00pm Supervisor: Dr. Justin Nodwell, Committee: Dr. Alan Davidson and Dr. Roman Melnyk MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Scavenger Receptor B1 Mediates the Uptake and Transcytosis of HDL in Brain Microvascular Endothelial Cells Karen Fung PhD Student Wednesday, May 10, 2017 - 4:00pm Supervisor: Dr. Greg Fairn, Committee: Dr. Reinhart Reithmeier and Dr. Tara Moriarty. MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Wednesday, May 3, 2017 - 4:00pm

PopNet: Visualizing Populations Javi Zhang PhD Student Wednesday, May 3, 2017 - 4:00pm Supervisor: John Parkinson, Committee: Alex Palazzo, Alex Ensminger MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

NUAK2 antagonizes Hippo in a feedforward loop that enforces YAP/TAZ signaling during tumorigenesis Mandeep Gill PhD Student Wednesday, May 3, 2017 - 4:00pm Supervisor: Liliana Attisano, Committee members: Dr. Trimble, Dr. Rotin, Dr. Angers MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Monday, May 1, 2017 - 10:00am

The physiology and habitat of the first cells on Earth Prof. William Martin Institute of Molecular Evolution, Heinrich-Heine-Universitaet Duesseldorf Monday, May 1, 2017 - 10:00am Host: Dr. Larry Moran CCBR Red Room Department of Biochemistry George Connell Lecture Poster available: W Martin Poster.pdf

Thursday, April 27, 2017 - 12:00pm

Unlocking our inner salamander: The path from scarring to perfect regeneration Dr. Joshua Currie Center for Regenerative Therapies, Dresden, Germany Thursday, April 27, 2017 - 12:00pm Host: Dr. Penney Gilbert and Dr. Alex Palazzo CCBR Red Room Department of Biochemistry George Connell Lecture Poster available: Poster_Joshua Currie.pdf

Wednesday, April 26, 2017 - 4:00pm

Global Analysis of Protein Abundance in the Budding Yeast Saccharomyces cerevisiae Brandon Ho PhD Student Wednesday, April 26, 2017 - 4:00pm Supervisor: Dr. Grant W. Brown, Committee: Dr. Amy Caudy and Dr. William Trimble MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Towards precise interpretation of EPR-based distance distributions from spin-labelled proteins. Aidin Balo Graduate Student Wednesday, April 26, 2017 - 4:00pm Supervisor: Dr. Oliver Ernst, Committee: Drs. Emil Pai & Scott Prosser MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar