Archived Biochemistry Seminars

Wednesday, July 24, 2024 - 1:00pm

Understanding the Regulation and Modification of Pel for use in the Pseudomonas aeruginosa Biofilm
Jaime Van Loon
Wednesday, July 24, 2024 - 1:00pm
Supervisor: Dr. P. Lynne Howell; Supervisory committee members: Dr. Trevor Moraes & Dr. Roman Melnyk
175 Elizabeth St, Toronto, ON M5G 2G3, Patient Support Centre, which is attached to the PGCRL SickKids building. PSC 12-14-001 Collaboration Room.
Department of Biochemistry Seminar
PhD Oral Seminar

Friday, June 21, 2024 - 2:00pm

CTLH complexes in secondary antibody diversification and ,their potential as targeted protein degradation effectors
Chetan Chana
Friday, June 21, 2024 - 2:00pm
Supervisor: Dr. Frank Sicheri; Supervisory Committee Members: Dr. Trevor Moraes, Dr. John Rubinstein
Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203
Department of Biochemistry Seminar
PhD Exam Seminar

Wednesday, May 29, 2024 - 12:00pm

Mechanisms of defense and counter-defense in the battle between bacteria and their viruses
Dr. Asma Hatoum-Aslan
Associate Professor of Microbiology ,University of Illinois, Urbana-Champaign
Wednesday, May 29, 2024 - 12:00pm
Host: Dr. Landon Getz Supervisor: Dr. Karen Maxwell
David Naylor Building, Rm6
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_Hatoum-1.pdf

Wednesday, May 22, 2024 - 1:00pm

Roles of NBEAL2, PIKFYVE, phosphoinositides and V-ATPase in megakaryocyte α-granule formation
Chien-Yi Lu
Wednesday, May 22, 2024 - 1:00pm
Supervisor: Dr. Walter Kahr ; Supervisory committee members: Dr. Sergio Grinstein, Dr. Greg Fairn
PGCRL Rm 3.9320, 3rd Fl. Multi-Media Room, 686 Bay St., Sickkids
Department of Biochemistry Seminar
PhD Oral Seminar

Wednesday, May 15, 2024 - 12:00pm

Building the mitotic spindle via microtubule nucleation
Sabine Petry, PhD
Princeton University
Wednesday, May 15, 2024 - 12:00pm
Host: Gaddy Rakhaminov (g.rakhaminov@mail.utoronto.ca)
C. David Naylor Building, Rm 6 6 Queen’s Park Crescent West
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_Petry.small_.pdf

Tuesday, May 7, 2024 - 2:00pm

Investigation of biomolecular condensate formation in the cellular response to genotoxic stress
Maria Tereshchenko
Tuesday, May 7, 2024 - 2:00pm
Supervisor: Dr. Hyun Lee; Supervisor Committee members: Dr Julie Forman-Kay and Dr. Daniel Durocher
MaRS, Room 1522
Department of Biochemistry Seminar
PhD Oral Seminar

Wednesday, May 1, 2024 - 12:00pm

A story of collaboration and discovery in Parkinson’s disease
Dr. Heidi McBride
Professor (Neurology and Neurosurgery, Medicine, McGill University)
Wednesday, May 1, 2024 - 12:00pm
Host: Prabhsimran Khroud
MSB 2172
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_McBride (1).pdf

Monday, April 22, 2024 - 2:00pm

Investigating the mechanisms that regulate the activity of the MUS81-EME1 endonuclease and the impact on cell fitness
Ying Wah Elizabeth Tse
Monday, April 22, 2024 - 2:00pm
Supervisor: Dr. Haley Wyatt; Supervisory Committee members: Dr. Trevor Moraes and Dr. Daniel Durocher
MaRS Room 1622
Department of Biochemistry Seminar
PhD Exam Seminar

Monday, April 22, 2024 - 10:00am

Biophysical Characterization of Prolyl hydroxylation-dependent HIF-1α Degradation
Wenguang He
Monday, April 22, 2024 - 10:00am
Supervisor: Dr. Michael Ohh, Co-Supervisor: Dr. Jeffrey Lee; Supervisory Committee members: Dr. Liliana Attisano & Dr. Mitsuhiko Ikura
CCBR Red Room
Department of Biochemistry Seminar
PhD Oral Seminar

Tuesday, April 9, 2024 - 2:00pm

Brain Development Mutations in a Tubulin Gene Result in Defective Ciliogenesis
Antonio Mollica
Tuesday, April 9, 2024 - 2:00pm
Supervisor: Supervisor: Dr. William Trimble; Co-supervisor:Ronald Cohn ; Superviosry member: Brian Ciruna Member: Andras Kapus
MSB Room 3278
Department of Biochemistry Seminar
PhD Oral Seminar

Tuesday, April 9, 2024 - 9:00am

The effects of post-translational modification on intrinsically disordered protein phase separation and nucleosome dynamics
Michael Nosella
Tuesday, April 9, 2024 - 9:00am
Supervisor: Dr. Julie Forman-Kay; Supervisory Committee Members; Dr. Alex Palazzo and Dr. Hyun (Kate) Lee
PGCRL Rm 3a, 3rd Fl, 686 Bay St., SickKids
Department of Biochemistry Seminar
PhD Oral Seminar

Wednesday, March 27, 2024 - 12:00pm

ALS and Neurodegeneration Starts at the Nuclear Pore: Insights and Therapy for ALS and Dementia Wednesday, March
Jeffrey D. Rothstein
Brain Science Institute and Dept of Neurology Johns Hopkins University ALS and
Wednesday, March 27, 2024 - 12:00pm
Host: Yifan (Eva) Wang (yifa.wang@mail.utoronto.ca)
PGCRL Auditorium, 686 Bay St., SickKids
Department of Biochemistry George Connell Lecture
Departmental Seminar
Poster available: PDF icon Connell poster_Rothstein.pdf

Wednesday, May 17, 2023 - 12:00pm

Information theory and signal processing for CFTR and other receptors
Dr. Andrew Eckford
Wednesday, May 17, 2023 - 12:00pm
Host: Nevraj Kejiou (nevraj kejiou@mail.utoronto.ca)
MSB 2172
Department of Biochemistry George Connell Lecture
Departmental Seminar
Poster available: PDF icon Connell poster_ECKFORD.pdf

Wednesday, May 10, 2023 - 12:00pm

High throughput functional annotation of pharmacogene variants using yeast activity assays
Dr. Maitreya Dunham
Professor of Genome Sciences, University of Washington
Wednesday, May 10, 2023 - 12:00pm
Host: Kate Jiang ((kate.jiang@mail.utoronto.ca)
MSB 2172
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_DUNHAM.pdf

Wednesday, November 30, 2022 - 12:00pm

Looking under the hood of cells: from single molecule dynamics to whole cell organelle reconstructions
DR. JENNIFER LIPPINCOTTSCHWARTZ
Howard Hughes Medical Institute, Janelia Research Campus
Wednesday, November 30, 2022 - 12:00pm
Host: Kyla Germain (kyla.germain@sickkids.ca)
Online - virtual
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_LIPPINCOTT-SCHWARTZ.pdf

Wednesday, October 19, 2022 - 12:00pm

Untangling Integrin Dynamics Using CryoEM
Melody Campbell, PhD
Fred Hutchinson Cancer Research Centre
Wednesday, October 19, 2022 - 12:00pm
Host: Yingke Liang (yingke.liang@mail.utoronto.ca)
MSB 2172
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell Lecture_CAMPBELL.pdf

Wednesday, September 28, 2022 - 1:00pm

Inner Workings of Channelrhodopsins and Brains
KARL DEISSEROTH
Stanford University, Howard Hughes Medical Institute
Wednesday, September 28, 2022 - 1:00pm
Host: Raphaella So
Online
Department of Biochemistry George Connell Lecture
Special Seminar
Poster available: PDF icon Connell poster_DEISSEROTH.pdf

Tuesday, June 28, 2022 - 9:00am

Deciphering the mechanisms of lipid homeostasis in organelles
Dr. Arun Peter
Department of Biology, University of Fribourg, Switzerland
Tuesday, June 28, 2022 - 9:00am
Host: Dr. Liliana Attisano
CCBR Red Room
Department of Biochemistry Seminar
Departmental Search Candidate

Thursday, June 23, 2022 - 10:00am

Metabolic Licensing of Beta-Cell Survival in Inflammation
Dr. Accalia Fu
Dana-Farber Cancer Institute & Harvard Medical School
Thursday, June 23, 2022 - 10:00am
Host: Dr. Liliana Attisano
CCBR Red Room
Department of Biochemistry Seminar
Departmental Search Candidate

Monday, June 20, 2022 - 2:00pm

Evolutionary persistence of DNA methylation for millions of years
Dr. Sandra Catania
Department of Biochemistry & Biophysics, University of California, San Francisco
Monday, June 20, 2022 - 2:00pm
Host: Dr. Liliana Attisano
CCBR Red Room
Department of Biochemistry Seminar
Departmental Search Candidate
Poster available: PDF icon Dr. Sandra Catania.pdf

Wednesday, March 9, 2022 - 12:00pm

Cell Organization by Liquid- Liquid Phase Separation
Michael K. Rosen
Wednesday, March 9, 2022 - 12:00pm
Host: Gaddy Rakhaminov (gaddy.rakhaminov@mail.utoronto.ca)
Online
Department of Biochemistry George Connell Lecture
Special Seminar
Poster available: PDF icon Connell poster_Michael K. Rosen.22.pdf

Wednesday, February 16, 2022 - 12:00pm

Genetic Systems for Rapid Mutation, Protein Evolution, and Biology
Chang C. Liu
Wednesday, February 16, 2022 - 12:00pm
Host: Peter Liang
Virtual
Department of Biochemistry George Connell Lecture
Departmental Seminar
Poster available: PDF icon Connell poster_LIU_2022.pdf

Wednesday, December 8, 2021 - 12:00pm

Tumorigenesis in the setting of DNA interstrand crosslink repair deficiency
Agata Smogorzewska, M.D., Ph.D.
Head, Laboratory of Genome Maintenance Rockefeller University
Wednesday, December 8, 2021 - 12:00pm
Host: Elizabeth Tse
Virtual
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_SMOGORZEWSKA-2.pdf

Wednesday, November 10, 2021 - 12:00pm

Noninvasive sensory stimulation to induce gamma entrainment and neuroprotection
DR. LI-HUEI TSAI
Director, Picower Institute for Learning & Memory Picower Professor of Neuroscience Co-Director, The Alana Down Syndrome Center Massachusetts Institute of Technology
Wednesday, November 10, 2021 - 12:00pm
Host: Raphaella So
Virtual
Department of Biochemistry George Connell Lecture
Departmental Seminar
Poster available: PDF icon Connell poster_TSAI.pdf

Wednesday, March 3, 2021 - 12:00pm

Clostridiodes difficile Infection: The Confluence of Pathogen, Host and Microbiota in the Gut
Vince Young, MD/PhD
Depts of Internal Medicine/Division of Infectious Diseases and Microbiology & Immunology, University of Michigan Medical School
Wednesday, March 3, 2021 - 12:00pm
Host: Simoun Icho (simoun.icho@mail.utoronto.ca)
Online, please contact host for more information
Department of Biochemistry George Connell Lecture
Special Seminar

Wednesday, February 24, 2021 - 1:00pm

Low temperature view of a cold sensor: structural insights into TRPM8 function and pharmacology
Melinda Diver
Department of Physiology, University of California, San Francisco, USA
Wednesday, February 24, 2021 - 1:00pm
Host: Dr. Justin Nodwell
https://us02web.zoom.us/j/83947741046?pwd=UFZML0xuU2lHaHFKbThieGhhMUZKdz09, Meeting ID: 839 4774 1046 Passcode: 5V9hUH
Biochemistry Faculty Search Seminar
Departmental Search Candidate

Tuesday, February 23, 2021 - 9:00am

Mechanism of co-translational protein targeting by the mammalian signal recognition particle to the endoplasmic reticulum
Ahmad Jomaa
Institute for Molecular Biology & Biophysics, Swiss Federal Institute of Technology, ETH Zurich, Switzerland
Tuesday, February 23, 2021 - 9:00am
Host: Dr. Justin Nodwell
https://us02web.zoom.us/j/87914630875?pwd=SEg3blhFQXpxeUtncnhDR0hIK0NoUT09, Meeting ID: 879 1463 0875 Passcode: 4h3PWq
Department of Biochemistry, Faculty Search Seminar
Departmental Search Candidate

Wednesday, February 17, 2021 - 1:00pm

Molecular assembly of measles virus and other emerging paramyxoviruses
Michael Norris
The Scripps Research Institute, La Jolla Institute for Immunology, California, USA
Wednesday, February 17, 2021 - 1:00pm
Host: Dr. Justin Nodwell
https://us02web.zoom.us/j/84307416155?pwd=RFVEajBNVGxSOEJaamNwSVR5Uzludz09, Meeting ID: 843 0741 6155 Passcode: 3u51DV
Department of Biochemistry, Faculty Search Seminar
Faculty Recruitment Seminar

Tuesday, February 16, 2021 - 9:00am

Structural basis of Ras inactivation by Neurofibromin 1
Dr. Malik Chaker-Margot
Biozentrum, Universität Basal Biozentrum, Universität Basal Biozentrum, Universität Basal Biozentrum, Universität Basal Biozentrum, Universität Basal
Tuesday, February 16, 2021 - 9:00am
Host: Dr. Justin Nodwell
https://us02web.zoom.us/j/86749911798?pwd=cUltWiswMU5BczBqbjFjZTZtQ3B3QT09, Meeting ID: 867 4991 1798 Passcode: ChrH31
Department of Biochemistry, Faculty Search Seminar
Departmental Search Candidate

Thursday, February 4, 2021 - 9:30am

Connecting the Dots: Orchestrating multiple substrates in bacterial secretion system.
Amit Meir
Boyer Center for Molecular Medicine, Yale School of Medicine, USA
Thursday, February 4, 2021 - 9:30am
Host: Dr. Justin Nodwell
https://us02web.zoom.us/j/83968785713?pwd=S1pyWmxQVFVPMkhSZVY2eWNFZ080QT09, Meeting ID: 839 6878 5713 Passcode: A9V9ra
Department of Biochemistry, Faculty Search Seminar
Departmental Search Candidate

Tuesday, February 2, 2021 - 9:00am

Dissecting the nature of the gamma-tubulin ring complex using cryo-EM and biochemical reconstitutions
Dr. Michael Wieczorek
Laboratory of Chemistry and Cell Biology, The Rockefeller University, New York, USA
Tuesday, February 2, 2021 - 9:00am
Host: Dr. Justin Nodwell
https://us02web.zoom.us/j/89167946405?pwd=ZEE0N1pJcWZoQ1NTZWZiWVJmdUhoQT09, Meeting ID: 891 6794 6405 Passcode: 0gGbS1
Department of Biochemistry, Faculty Search Seminar
Departmental Search Candidate

Thursday, December 17, 2020 - 1:00pm

Obesity-driven Immunometabolic Activation of Myeloid Cells
Parastoo Boroumand
Thursday, December 17, 2020 - 1:00pm
Supervisor: Dr. Amira Klip, Co-Supervisor: Dr. Stephan Giradin Supervisory Committee Members: Dr. Khosrow Adeli, Hoon-ki Sung
Remote - Please contact students advisor
Department of Biochemistry Seminar
PhD Oral Seminar

Wednesday, November 18, 2020 - 12:00pm

Combinatorial selection drives pathogen evolution in environmental reservoirs
Tamara O’Connor
Department of Biological Chemistry, Johns Hopkins University School of Medicine
Wednesday, November 18, 2020 - 12:00pm
Host: Shayna Deecker (shayna.deecker@utoronto.ca)
VIRTUAL LECTURE. Contact host for details
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_OCONNOR.pdf

Wednesday, September 23, 2020 - 12:00pm

Proteopathic seeding in neurodegenerative disease
BRYON CAUGHEY
Senior Investigator, Rocky Mountain Laboratories, NIAID, NIH
Wednesday, September 23, 2020 - 12:00pm
Host: Department of Biochemistry
VIRTUAL LECTURE. Contact host for details - Raphaella So (raphaella.so@mail.utoronto.ca)
Department of Biochemistry George Connell Lecture
Invited Speaker Seminar
Poster available: PDF icon Connell poster_CAUGHEY.smll_.pdf

Wednesday, June 24, 2020 - 12:00pm

Quantum Biology Guest Panel Discussion
Drs. A.Olaya-Castro, M Miller, M.Bordonaro
University College London, University of Toronto, Geisinger Commonwealth School of Medicine
Wednesday, June 24, 2020 - 12:00pm
Host: Claire McMurray & James Otis
Zoom Link
Department of Biochemistry, Graduate Student Seminar Series
Special Seminar

Wednesday, June 17, 2020 - 12:00pm

The Epidemiology, Big Data of Covid Panel Discussion
A. Levin, J. Heffer, Isha Berry, Jean-Paul Soucy
Henry Ford Health, York University, University of Toronto
Wednesday, June 17, 2020 - 12:00pm
Host: Nick Demers
Zoom Link
Department of Biochemistry, Graduate Student Seminar Series
Special Seminar

Wednesday, June 10, 2020 - 12:00pm

12: LC-MS-based metabolomics: basics of the instrumentation 12:30 Research at Repare Therapeutics Inc
Dr. Yunoung Li then Dr. David Gallo
University of Toronto (Li) , Repare Therapeutics Inc (Gallo)
Wednesday, June 10, 2020 - 12:00pm
Host: Doorsa Tarazi and Amogh Natu Supervisor: Dr. Jason Maynes, Repare Therapeutics Inc.
Zoom Link
Department of Biochemistry, Graduate Student Seminar Series
Special Seminar

Wednesday, May 13, 2020 - 12:00pm

Keeping Up with "Kwarantine" Talk Show
Special Guests: Drs. Trevor Moraes & Tomas Gverdyz
University of Toronto & PPD Laboratories (Wisconsin)
Wednesday, May 13, 2020 - 12:00pm
Host: Shivneet Gill (Grad Student from R. Melnyk Lab)
By Zoom Invitation
Department of Biochemistry Seminar
Special Seminar

Wednesday, April 29, 2020 - 12:00pm

Elucidating the mechanism of multi drug resistant efflux pump inhibitor peptides
Chloe Mitchell
Wednesday, April 29, 2020 - 12:00pm
Supervisor: Dr. Charles Deber
Online seminar
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Monday, March 23, 2020 - 10:30am

Macrophage Surveillance and Immunity: Eating, Drinking, and Digesting
Philip Ostrowski
Monday, March 23, 2020 - 10:30am
Supervisor: Dr. Sergio Grinstein
Seminar will be shown online
Department of Biochemistry Seminar
PhD Oral Seminar

Monday, March 16, 2020 - 9:10am

Chemical warfare in the phage-host evolutionary arms race
Dr. Karen Maxwell
Monday, March 16, 2020 - 9:10am
Host: Dr. Grant Brown
Join Zoom Meeting https://zoom.us/j/902556130?pwd=bGpmSXBVbGY2aVR1OSs2TmtLc0VHQT09 Meeting ID: 902 556 130 Password: 753347 One tap mobile +16475580588,,902556130# Canada Dial by your location +1 647 558 0588 Canada Meeting ID: 902 556 130
Department of Biochemistry Seminar
Departmental Search Candidate

Wednesday, March 11, 2020 - 12:00pm

The mechanism of nickel activated DNA binding by the NikR transcriptional regulator from Helicobacter pylori
Karina Baksh
Wednesday, March 11, 2020 - 12:00pm
Supervisor: Dr. Deborah Zamble; Supervisory Committee Members: Dr. Trevor Moraes, Dr. Gil Prive
PGCRL Auditorium, 686 Bay St., SickKids
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Tuesday, February 25, 2020 - 9:00am

Mechanistic insights into the activation and modulation of the Wasabi Receptor
Jianhua Zhao, Ph.D
University of California, San Francisco, USA
Tuesday, February 25, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 2173
Department of Biochemistry Seminar
Departmental Search Candidate

Thursday, February 20, 2020 - 9:00am

The cryo-EM structure of human CST reveals a two-megadalton decameric assembly bound to telomeric DNA
Ci Ji Lim, Ph.D
Biochemistry, University of Colorado Boulder, Colorado, USA
Thursday, February 20, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 2173
Department of Biochemistry Seminar
Departmental Search Candidate

Wednesday, February 12, 2020 - 12:00pm

The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus
Kathleen Orrell
Wednesday, February 12, 2020 - 12:00pm
Supervisor: Dr. Roman Melnyk, Supervisory Committee: Dr. Christine Bear, Dr. Trevor Moraes
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Wednesday, February 5, 2020 - 12:00pm

Structural and functional characterization of a conserved stress response kinase
Zhe (Jay) Yin
Wednesday, February 5, 2020 - 12:00pm
Supervisor: Dr. Frank Sicheri, Supervisory Committee Members: Dr. Grant Brown, Dr. Jeff Wrana
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Tuesday, February 4, 2020 - 9:00am

Snapshots of Bacterial and Mammalian Co-translational Membrane-Targeting Complexes Visualized Using Electron Cryomicroscopy
Ahmad Jomaa, Ph.D.
ETH Zurich, Switzerland
Tuesday, February 4, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 2173
Department of Biochemistry Seminar
Departmental Search Candidate

Wednesday, January 29, 2020 - 12:00pm

Pyruvate Kinase Regulates mRNA Translation in a Glucose-Dependent Fashion
Nevraj Kejiou
Wednesday, January 29, 2020 - 12:00pm
Supervisor: Dr. Alex Palazzo, Supervisory Committee Members: Dr's Angus McQuibban, Craig Smibert, Amy Caudy
PGCRL Auditorium, 686 Bay St., SickKids
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Tuesday, January 28, 2020 - 9:00am

CasX enzymes comprise a distinct family of RNA-guided genome editors
Jun-Jie (Gogo) Liu, PhD
Lawrence Berkeley National Laboratory Dept. of Molecular Cell Biology | University of California, Berkeley, USA.
Tuesday, January 28, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 2173
Department of Biochemistry Seminar
Faculty Recruitment Seminar

Wednesday, January 22, 2020 - 12:00pm

Leveraging Legionella pneumophila CRISPR-Cas to identify exogenous threats to pathogen survival
Shayna Deecker, PhD
Wednesday, January 22, 2020 - 12:00pm
Supervisor: Dr. Alexander Ensminger, Supervisory Committee members: Dr. Alan Davidson and Dr. William Navarre
PGCRL Auditorium, 686 Bay St., SickKids
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

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