Previous Seminars

Friday, March 23, 2018 - 2:00pm

Monday, March 26, 2018 - 11:00am

Monday, March 26, 2018 - 12:30pm

Microcolonies of human embryonic stem cells as models of early embryonic patterning Dr. Eric Siggia Viola Ward Brinning and Elbert Calhoun Brinning Professor at Rockefeller University Monday, March 26, 2018 - 12:30pm Host: Dr. Sidhartha Goyal MSB 2170 Medicine by Design Global Speaker Series Special Seminar Co-sponsor: Ontario Institute for Regenerative Medicine Poster available: GlobalSpeakerSeries Eric Siggia poster.pdf

Monday, March 26, 2018 - 1:00pm

Microbial Control of Intestinal Immune Homeostasis Arthur Mortha, PhD Department of Immunology, University of Toronto Monday, March 26, 2018 - 1:00pm Host: Dr. John Parkinson PGCRL Event Rooms 3A/3B (03.9310, 3rd Floor) Molecular Medicine Seminar Series Departmental Seminar Poster available: MM Seminar - Dr. Mortha March 26.pdf

Monday, March 26, 2018 - 4:00pm

Structure-based Design of Coronavirus Vaccine Antigens Jason S. McLellan, PhD Associate Professor, Department of Molecular Biosciences, The University of Texas at Austin Monday, March 26, 2018 - 4:00pm Host: Drs. J. Lee & J P Julien, jeff.lee@utoronto.ca & jean-philippe.julien@sickkids.ca MSB 2170 Laboratory Medicine and Pathobiology Seminar Invited Speaker Seminar Poster available: Poster JMcLellan.pdf

Tuesday, March 27, 2018 - 11:00am

Cell wall signaling: mechanisms that regulate plant cell wall synthesis and secretion Dr. Heather E. McFarlane ARC DECRA Fellow, School of Biosciences, University of Melbourne Tuesday, March 27, 2018 - 11:00am Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology Special Seminar Poster available: Dr. Heather McFarlane Seminar Poster.pdf

Wednesday, March 28, 2018 - 9:00am

Host/Candida albicans interactions: commensal colonization or disease? Dr. Carol Kumamoto School of Medicine, Tufts University Wednesday, March 28, 2018 - 9:00am Host: Dr. Leah Cowen CCBR Red Room Department of Molecular Genetics Invited Speaker Seminar Poster available: Kumamoto Poster.pdf

Wednesday, March 28, 2018 - 12:00pm

Wednesday, March 28, 2018 - 1:00pm

Dissecting Mechanisms of Echinocandin Drug Resistance and Filamentation in the Fungal Pathogen Candida albicans Elizabeth Polvi PhD Candidate Wednesday, March 28, 2018 - 1:00pm Supervisor: Dr. Leah Cowen MSB 4171 Department of Molecular Genetics PhD Oral Seminar Poster available: Polvi Poster.pdf

Wednesday, March 28, 2018 - 4:00pm

Thursday, March 29, 2018 - 11:00am

Why is it hard to treat Cancer? Nano- and microscale technologies that offer a solution Shiladitya Sengupta, PhD, MSc Associate Bioengineer, Medicine, Brigham and Women’s Hospital, Dana-Farber/Harvard Cancer Center | Assistant Professor, Medecine, Harvard Medical School and Health Sciences and Technology, Harvard-MIT | Cambridge, MA Thursday, March 29, 2018 - 11:00am Host: Warren Chan, PhD, Professor and Chair, Institute of Biomaterials and Biomedical Engineering (IBBME), The Donnelly Centre, Department of Materials Sciences and Engineering, Department of Chemistry, Department of Chemical Engineering CCBR Red Room Donnelly Seminar Series Invited Speaker Seminar Poster available: S Sengupta 29 March 2018 donnelly poster.compressed.pdf

Thursday, March 29, 2018 - 1:00pm

Thursday, March 29, 2018 - 3:00pm

Using recombinant malaria proteins to detect and target human cancers Dr. Mads Daugaard Senior Research Scientist, Vancouver Prostate Centre, Head Molecular Pathology and Cell Imaging Core Facility, Vancouver Prostate Centre, Assistant Professor, Department of Urologic Sciences, University of British Columbia Thursday, March 29, 2018 - 3:00pm Host: Dr. Brent Derry PG CRL Auditorium, 686 Bay St., SickKids Co-sponsor: Garron Family Cancer Centre - SickKids Poster available: MADS_DAUGAARD_Seminar.pdf

Monday, April 2, 2018 - 11:00am

Multitasking: coordination of stress responses and seed maturation by abscisic acid transcription factor networks Dr. Liang Song Salk Institute for Biological Studies Monday, April 2, 2018 - 11:00am Host: Cell and Systems Biology Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology Special Seminar Poster available: Dr. Liang Song Seminar Poster.pdf

Major vault protein holds the key for DDR1-β1 integrin interaction Dr. Nuno Coelho Faculty of Dentistry, University of Toronto Monday, April 2, 2018 - 11:00am Fitzgerald Building, Room #237 Matrix Dynamics Group Seminar Research Group Seminar

Tuesday, April 3, 2018 - 10:00am

Function and regulation of the microRNA-mediated gene silencing pathway Dr. Martin Simard St-Patrick Research Group in Basic Oncology, CRCHU de Québec-Université Laval Tuesday, April 3, 2018 - 10:00am Host: Dr. Julie Claycomb CCBR Red Room Department of Molecular Genetics Invited Speaker Seminar Poster available: Simard Poster.pdf

Tuesday, April 3, 2018 - 1:00pm

Characterization of two opposing small RNA pathways required for germline homeostasis in Caenorhabditis elegans Monica Wu PhD Candidate Tuesday, April 3, 2018 - 1:00pm Supervisor: Dr. Julie Claycomb MSB 2172 Department of Molecular Genetics PhD Oral Seminar Poster available: Wu Poster.pdf

Tuesday, April 3, 2018 - 4:00pm

Using C. elegans to understand and treat cerebral cavernous malformations W. Brent Derry Ph.D Senior Scientist, Hospital for Sick Children Professor, Department of Molecular Genetics Tuesday, April 3, 2018 - 4:00pm MSB 2170 Pharmacology and Toxicology Seminar Special Seminar Poster available: Derry Poster April 3.pdf

Wednesday, April 4, 2018 - 3:00pm

Mechanisms of longevity and cancer resistance in long-lived mammals Dr. Vera Gorbunova Doris Johns Cherry Professor of Biology, Co-director Rochester Aging Research Centre, University of Rochester, Department of Biology Wednesday, April 4, 2018 - 3:00pm Host: Dr. Brent Derry Hospital for Sick Children, 555 University Avenue, Room 1246 Black Wing Developmental and Stem Cell Biology Invited Speaker Seminar Poster available: Vera Gorbunova Seminar Announcement.pdf

Wednesday, April 4, 2018 - 4:00pm

Thursday, April 5, 2018 - 12:00pm

How do mechanical forces sculpt tissues? Dr. Lisa Manning Department of Physics, Syracuse University Thursday, April 5, 2018 - 12:00pm Host: Dr. Rodrigo Fernandez-Gonzalez McLennan Physical Laboratories, Room MP606 BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: LManning_April5.pdf

In vitro epithelial cell outcome measures; What is not current Dr. Theo Moraes Thursday, April 5, 2018 - 12:00pm Hospital for Sick Children, 555 University Avenue, Room 1527, Hill Wing Cystic Fibrosis Seminar

Thursday, April 5, 2018 - 1:30pm

Unexpected Catalysis for RNA and DNA: Roles in Biology? Dr. Dipankar Sen Dept. of Chemistry and Dept. of Molecular Biology & Biochemistry; Simon Fraser University Thursday, April 5, 2018 - 1:30pm Host: Dr. Charles Boone and Dr. Sachdev Sidhu MSB 2172 Department of Molecular Genetics Invited Speaker Seminar Poster available: Sen Poster.pdf

Thursday, April 5, 2018 - 4:00pm

The Epigenetic Landscape of Cancer Andrew P. Feinberg, MD, MPH Bloomberg Distinguished Professor, Johns Hopkins University Schools of Medicine, Engineering, and Public Health Thursday, April 5, 2018 - 4:00pm Host: Dr. Mathieu Lupien PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 Princess Margaret Seminar Series

Translational control of cancer and Fragile-X syndrome via elF4E Nahum Sonenberg, OC FRS FRSC Rosalind and Morris Goodman Cancer Research Centre, Department of Biochemistry, McGill University Thursday, April 5, 2018 - 4:00pm Host: Julie Forman-Kay, PhD PG CRL Auditorium, 686 Bay St., SickKids The Aser Rothstein Lecture Series Invited Speaker Seminar Poster available: 2018Apr5_AserRothstein.pdf

Friday, April 6, 2018 - 10:00am

Metabolic flexibility in breast cancer progression Dr. Julie St-Pierre Ottawa Institute of Systems Biology Friday, April 6, 2018 - 10:00am Host: Dr. Jason Moffat MSB 4279 Department of Molecular Genetics Invited Speaker Seminar Poster available: St-Pierre Poster1.pdf

Friday, April 6, 2018 - 12:00pm

Friday, April 6, 2018 - 1:00pm

Yeast Two-Hybrid is an Effective Platform for the Discovery of Novel Inhibitors of Human Deubiquitinases Natasha Pascoe PhD Candidate Friday, April 6, 2018 - 1:00pm Supervisor: Drs. Charles Boone & Sachdev Sidhu CCBR Red Room Department of Molecular Genetics PhD Oral Seminar Poster available: Pascoe Poster.pdf

Friday, April 6, 2018 - 1:30pm

Identification of fitness genes and genotype-specific vulnerabilities using functional genetic screens in human cancer cells Megha Chandrashekhar PhD Candidate Friday, April 6, 2018 - 1:30pm Supervisor: Dr. Jason Moffat MSB 4279 Department of Molecular Genetics PhD Oral Seminar Poster available: Chandrashekar Poster.pdf

RTKs and all that jazz: signals that instruct how to form the face Dr. Philippe Soriano Professor, Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai Friday, April 6, 2018 - 1:30pm Host: Dr. Janet Rossant Hospital for Sick Children, 555 University Avenue, Room 1246 Black Wing Developmental and Stem Cell Biology Special Seminar Poster available: Philippe Soriano Seminar Announcement.pdf

As the fat flies: lipid droplets as modulators of histone metabolism. Michael Welte, PhD Department of Biology, University of Rochester Friday, April 6, 2018 - 1:30pm PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Welte.pdf

Monday, April 9, 2018 - 11:00am

Decoding cell surface receptor interaction networks by system genetics approaches Dr. Youssef Belkhadir Gregor Mendel Institute of Molecular Plant Biology Monday, April 9, 2018 - 11:00am Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology Departmental Search Candidate Poster available: Dr. Youssef Belkhadir seminar poster.pdf

About the stress and strain of biologists measuring fibroblast contraction Boris Hinz, Ph.D. Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, Faculty of Dentistry, University of Toronto Monday, April 9, 2018 - 11:00am Fitzgerald Building, Room #237 Matrix Dynamics Group Seminar Research Group Seminar

Monday, April 9, 2018 - 1:00pm

Nature's Environmental Stressors: Studies & Applications to Novel Anti-Cancer Therapies & Research Tools Kevin Gardner, PhD Einstein Professor of Chemistry, Director of the Structural Biology Initiative of the CUNY Advanced Science Research Centre Monday, April 9, 2018 - 1:00pm Host: Dr. Lewis Kay PGCRL Event Rooms 3A/3B (03.9310, 3rd Floor) Molecular Medicine Seminar Series Invited Speaker Seminar Poster available: MM Seminar - Dr. Gardner April 9.pdf

Monday, April 9, 2018 - 2:30pm

Atomic-Resolution Map of the Interactions between Amloid Inhibitors and Beta Amyloid Peptides in the Monomer and Protofibril States Dr. Giuseppe Melacini Professor of Chemistry and Chemical Biology, McMaster University Monday, April 9, 2018 - 2:30pm Host: Dr. Avi Chakrabartty MaRS- TMDT R# 4-204, 4th floor Department of Medical Biophysics Seminar Special Seminar Poster available: MBP - Special Seminar - Dr. Giuseppe Melacini.pdf

Monday, April 9, 2018 - 4:00pm

Crosstalk between protein synthesis and cancer energetics DSR Sarma Lectureship in Oncologic Pathology, Ivan Topisirovic, MD, PhD Ivan Topisirovic MD, PhD Investigator, Lady Davis Institute, SMBD Jewish General Hospital, Assistant Professor, Dept of Oncology, McGill University Monday, April 9, 2018 - 4:00pm Host: Michael Ohh, PhD MSB 2170 Laboratory Medicine and Pathobiology Seminar Departmental Seminar Poster available: DSR Sarma 2018.pdf

Tuesday, April 10, 2018 - 12:00pm

WORKSHOP: Innovative high-throughput technologies for drug screening and cell imaging Network Biology Collaborative Centre *Registration Required* Tuesday, April 10, 2018 - 12:00pm Host: Network Biology Collaborative Centre Research Institute Location TBA Workshop Poster available: NBCC_workshop_AP10_18_schedule.pdf

Tuesday, April 10, 2018 - 2:00pm

Multi-layered signaling networks in uncovering hidden interactions and key regulators in cancer, inflammatory bowel disease and during infection Tamás Korcsmáros, PhD Research Leader, The Quadram Institute | Computational Biology Fellow, Earlham Institute, Norwich Research Park, Norfolk, UK Tuesday, April 10, 2018 - 2:00pm Host: Gary G. Bader, PhD | Ontario Research Chair in Biomarkers of Disease | Professor, The Donnelly Centre, Department of Molecular Genetics, Department of Computer Science CCBR Red Room Invited Speaker Seminar Poster available: Tamás Korcsmáros April 10 2018 poster.compressed.pdf

Tuesday, April 10, 2018 - 4:00pm

Optimizing pharmacotherapy of neuropsychiatric symptoms associated with neurodegenerative disease Krista L. Lanctôt PhD Senior Scientist, Hurvitz Brain Sciences Program, Sunnybrook Research Institute Professor of Psychiatry and Pharmacology, University of Toronto Tuesday, April 10, 2018 - 4:00pm Host: Dr. Walter Swardfager MSB 4171 Pharmacology and Toxicology Seminar Poster available: Lanctot Poster April 10.pdf

Wednesday, April 11, 2018 - 9:00am

Metabolomics Analysis Reveals Novel Aspects of 2-Hydroxyglutarate Homeostasis and Links Citramalate to Branched Chain Amino Acid Metabolism Olga Zaslaver PhD Candidate Wednesday, April 11, 2018 - 9:00am Supervisor: Dr. Amy Caudy MSB 4171 Department of Molecular Genetics PhD Oral Seminar Poster available: Zaslaver Poster.pdf

Wednesday, April 11, 2018 - 10:00am

Wednesday, April 11, 2018 - 12:00pm

Kinase and pseudokinase signalling networks in human cancer Dr. Roger Daly Head of Department of Biochemistry and Molecular Biology, Monash University Wednesday, April 11, 2018 - 12:00pm Host: Dr. Daniel Schramek Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 Lunenfeld-Tanenbaum Seminar Series Invited Speaker Seminar Poster available: Roger Daly poster.pdf

Wednesday, April 11, 2018 - 1:00pm

Wednesday, April 11, 2018 - 4:00pm

Moving forward with PilT Matthew McCallum PhD Student Wednesday, April 11, 2018 - 4:00pm Supervisor: Dr. P. Lynne Howell, Committee: Dr. Justin Nodwell, Dr. John Rubinstein, and Dr. Lori L. Burrows MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Uncovering fundamental principles of septins through in vitro polymerization Forooz Soroor PhD Student Wednesday, April 11, 2018 - 4:00pm Supervisor: Dr. William Trimble, Committee: Dr. Julie Brill and Dr. John Rubinstein MSB 2172 Department of Biochemistry, Graduate Student Seminar Series Departmental Seminar

Discovering the chemistries of our hidden microbial self Dr. Nathan Magarvey Dept. of Biochemistry and Biomedical Sciences; McMaster University Wednesday, April 11, 2018 - 4:00pm Host: Dr. Amy Caudy CCBR Red Room Department of Molecular Genetics Invited Speaker Seminar Poster available: Magarvey Poster.pdf

Thursday, April 12, 2018 - 9:00am

Rett Syndrome: Closing the Gap to Clinical Trials Alan K. Percy, MD Professor, Pediatrics, Neurology, Neurobiology, Genetics, and Psychology Acting Director, Civitan International Research Center, University of Alabama at Birmingham Thursday, April 12, 2018 - 9:00am Host: Monica Justice, PhD Hospital for Sick Children, 555 University Avenue, Room 1246 Black Wing Poster available: AlanPercy.pdf