Archived Biochemistry Seminars

Thursday, February 20, 2020 - 9:00am

The cryo-EM structure of human CST reveals a two-megadalton decameric assembly bound to telomeric DNA
Ci Ji Lim, Ph.D
Biochemistry, University of Colorado Boulder, Colorado, USA
Thursday, February 20, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 2173
Department of Biochemistry Seminar
Departmental Search Candidate

Wednesday, February 12, 2020 - 12:00pm

The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus
Kathleen Orrell
Wednesday, February 12, 2020 - 12:00pm
Supervisor: Dr. Roman Melnyk, Supervisory Committee: Dr. Christine Bear, Dr. Trevor Moraes
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Wednesday, February 5, 2020 - 12:00pm

Structural and functional characterization of a conserved stress response kinase
Zhe (Jay) Yin
Wednesday, February 5, 2020 - 12:00pm
Supervisor: Dr. Frank Sicheri, Supervisory Committee Members: Dr. Grant Brown, Dr. Jeff Wrana
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Tuesday, February 4, 2020 - 9:00am

Snapshots of Bacterial and Mammalian Co-translational Membrane-Targeting Complexes Visualized Using Electron Cryomicroscopy
Ahmad Jomaa, Ph.D.
ETH Zurich, Switzerland
Tuesday, February 4, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 2173
Department of Biochemistry Seminar
Departmental Search Candidate

Wednesday, January 29, 2020 - 12:00pm

Pyruvate Kinase Regulates mRNA Translation in a Glucose-Dependent Fashion
Nevraj Kejiou
Wednesday, January 29, 2020 - 12:00pm
Supervisor: Dr. Alex Palazzo, Supervisory Committee Members: Dr's Angus McQuibban, Craig Smibert, Amy Caudy
PGCRL Auditorium, 686 Bay St., SickKids
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Tuesday, January 28, 2020 - 9:00am

CasX enzymes comprise a distinct family of RNA-guided genome editors
Jun-Jie (Gogo) Liu, PhD
Lawrence Berkeley National Laboratory Dept. of Molecular Cell Biology | University of California, Berkeley, USA.
Tuesday, January 28, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 2173
Department of Biochemistry Seminar
Faculty Recruitment Seminar

Wednesday, January 22, 2020 - 12:00pm

Leveraging Legionella pneumophila CRISPR-Cas to identify exogenous threats to pathogen survival
Shayna Deecker, PhD
Wednesday, January 22, 2020 - 12:00pm
Supervisor: Dr. Alexander Ensminger, Supervisory Committee members: Dr. Alan Davidson and Dr. William Navarre
PGCRL Auditorium, 686 Bay St., SickKids
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar
Structure of the Yeast V1-ATPase
Thamiya Vasanthakumar, PhD program
Wednesday, January 22, 2020 - 12:00pm
Supervisor: Dr. John Rubinstein, Supervisory Committee Members: Dr. Trevor Moraes, Dr. Christine Bear
PGCRL Auditorium, 686 Bay St., SickKids
Department of Biochemistry Seminar
Departmental Seminar

Tuesday, January 21, 2020 - 9:00am

Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex
Dr. Monica Pillon
National Institutes of Health (NIH), National Institute of Environmental Health Science (NIEHS), Signal Transduction Laboratory, USA.
Tuesday, January 21, 2020 - 9:00am
Host: Dr. Justin Nodwell
MSB 4279
Department of Biochemistry Seminar
Faculty Recruitment Seminar

Wednesday, January 8, 2020 - 4:00pm

The Legionella Dot/lcm Type IV secretion system: polarity guided cryo-EM analysis
Dr. Joseph Vogel
Washington University, Department of Molecular Microbiology
Wednesday, January 8, 2020 - 4:00pm
Host: Dr. Alex Ensminger
MaRS West Tower, Room 1522
Department of Biochemistry Seminar
Special Seminar
Poster available: PDF icon Vogel_Poster.pdf

Wednesday, December 18, 2019 - 12:00pm

Initiating a neuronal reprogramming strategy targeting the motor cortex in a mouse model of ALS
EunJee Park
PhD
Wednesday, December 18, 2019 - 12:00pm
Supervisor: Dr. Carol Schuurmans , Supervisory Committee members: Dr. Liliana Attisano and Dr. Isabelle.Aubert
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Wednesday, December 11, 2019 - 12:00pm

Neurog2 and Ascl1 co-expression defines a population of Notch ligand-expressing niche cells that control cortical neurogenesis.
Sisu Han
PhD
Wednesday, December 11, 2019 - 12:00pm
Supervisor: Dr. Carol Schuurmans, Supervisory Committee members: Dr. David Andrews, Dr. JoAnne McLaurin
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Thursday, December 5, 2019 - 2:00pm

Revisiting natural products to address the antibiotic resistance crisis
Dr. Gerry Wright
Department of Biochemistry and Biomedical Sciences, McMaster University
Thursday, December 5, 2019 - 2:00pm
Host: Martin Daniel-Ivad
MSB 2173
Department of Biochemistry Seminar
Departmental Seminar
Poster available: PDF icon Seminar Dec 5 -Gerry Wright.pdf

Thursday, December 5, 2019 - 9:30am

STRUCTURAL CHARACTERIZATION OF PHOTORECEPTOR COMPLEXES BY EPR SPECTROSCOPY
Wei-Lin Ou
Thursday, December 5, 2019 - 9:30am
Supervisor: Dr. Oliver Ernst
MSB 4279
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Wei-Lin.Ou_.pdf

Thursday, December 5, 2019 - 9:00am

Uncovering ‘Cryptic’ Natural Products from Streptomyces Bacteria
Martin Daniel-Ivad
Thursday, December 5, 2019 - 9:00am
Supervisor: Dr. Justin Nodwell
Medical Sciences Building, Room 3278
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Martin.Daniel.Ivad_.pdf

Wednesday, December 4, 2019 - 2:00pm

Structure and function of the RING-like protein RTF2
Andrew Zhai
Wednesday, December 4, 2019 - 2:00pm
Supervisor: Dr. Gil Prive
CCBR Red Room
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Andrew.Zhai_.pdf

Wednesday, December 4, 2019 - 12:00pm

Genome wide CRISPR screens as a tool to interrogate the Hippo pathway
Sabrina Sen
PhD
Wednesday, December 4, 2019 - 12:00pm
Supervisor: Dr. Liliana Attisano, Supervisory Committee Members: Dr. Igor Stagljar, Dr. Stephane Angers, Dr. Andras Kapus
Sandford Fleming Buidling, Room 1101
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Monday, December 2, 2019 - 9:00am

Mechanistic and Regulatory Insights into the Biosynthesis of the Pseudomonas aeruginosa Biofilm Exopolysaccharide Pel
Gregory Whitfield
Monday, December 2, 2019 - 9:00am
Supervisor: Dr. Lynne Howell
CCBR Black Room
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Gregory.Whitfield.pdf

Wednesday, November 27, 2019 - 12:00pm

Examining the Molecular Basis of Heme Acquisition in Acinetobacter baumannii
Tom Bateman
PhD
Wednesday, November 27, 2019 - 12:00pm
Supervisor: Dr. Trevor Moraes, Supervisory Committee Members: Dr. Lynne Howell and Dr. Scott Gray-Owen
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar
Unraveling the Molecular Gating Mechanism of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
Zhi Wei Zeng
PhD
Wednesday, November 27, 2019 - 12:00pm
Supervisor: Dr. Régis Pomès, Supervisory Committee members: Dr. Charles Deber, Dr. Oliver Ernst
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Wednesday, November 13, 2019 - 9:00am

Regulation of a Downstream Effector (DIAPH) of RhoA Signaling in Ciliogenesis and Maintenance of the Primary Cilia
Oliva Palander
Wednesday, November 13, 2019 - 9:00am
Supervisor: Dr. William Trimble
CCBR Red Room
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Oliva_.Palander.pdf

Wednesday, November 6, 2019 - 12:00pm

Inactivation of Rho-family GTPases by Burkholderia cenocepacia induces a WASH-mediated actin polymerization that delays phagosome maturation
Glenn Walpole - PhD (MD/PhD) program
Wednesday, November 6, 2019 - 12:00pm
Supervisor: Supervisor: Sergio Grinstein, Co-Supervisor: John Brumell, Supervisory Committee members: Peter Kim, Mathieu Lemaire
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar
Characterizing a lipid transfer protein at endoplasmic reticulum-peroxisome contact sites
Derrick Cheng
Wednesday, November 6, 2019 - 12:00pm
Supervisor: Dr. Peter Kim , Supervisory Committee members: Dr. Alex Palazzo, Dr. William Trimble
MSB 2170
Department of Biochemistry Seminar

Wednesday, October 30, 2019 - 12:00pm

What if Alzheimer's disease was not caused by amyloid?
Dr. Karl Herrup
Professor of Neurobiology, University of Pittsburgh Medical School
Wednesday, October 30, 2019 - 12:00pm
Host: Raphaella So
MSB 2170
Department of Biochemistry George Connell Lecture
Poster available: PDF icon Connell 2019_Karl Herrup.pdf

Wednesday, October 23, 2019 - 12:00pm

Protozoa in the microbiome and their interactions with other gut microbiota
Ana Popovic - PhD
Wednesday, October 23, 2019 - 12:00pm
Supervisor: John Parkinson, Supervisory Committee Members: Alex Ensminger, Leah Cowen
MSB 2170
Department of Biochemistry Seminar
Departmental Seminar

Wednesday, October 16, 2019 - 12:00pm

Regulation of protein functions by 3’UTRs
Dr. Christine Mayr
Sloan Kettering Institute, New York
Wednesday, October 16, 2019 - 12:00pm
Host: Nevraj Kejiou
MSB 2170
Biochemistry George Connell Lectures Seminars
Poster available: PDF icon Connell poster_MAYR.pdf

Wednesday, October 9, 2019 - 12:00pm

Direct inhibition of BAX and BAK for protection against apoptosis initiation at the mitochondria
Justin Pogmore
Wednesday, October 9, 2019 - 12:00pm
Supervisor: Dr. David Andrews, Committee Members: Dr. Peter Kim, Dr. Sergio Grintstein
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar
Astral microtubules regulate cortical actin during cytokinesis
Anan Chen
Wednesday, October 9, 2019 - 12:00pm
Supervisor: Dr. Andrew Wilde, Committee Members: Dr. Alex Palazzo, Dr. Boris Hinz, Dr. William Trimble
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Wednesday, October 2, 2019 - 12:00pm

Poster Winners from the Annual Biochemistry Retreat
Poster Winners
Wednesday, October 2, 2019 - 12:00pm
Supervisor: Dr. Alex Palazzo, Graduate Coordinator
MSB 2170
Department of Biochemistry, Graduate Student Seminar Series
Departmental Seminar

Friday, September 20, 2019 - 2:00pm

Recruitment and Mechanism of the Bacterial Type IV Pilus Motors
Matthew McCallum
Friday, September 20, 2019 - 2:00pm
Supervisor: Dr. Lynne Howell
MSB 2170
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Matthew.McCallum.pdf

Wednesday, September 18, 2019 - 12:00pm

The social and chemical lives of actinomycete bacteria
Dr. Matt Traxler
UC Berkeley
Wednesday, September 18, 2019 - 12:00pm
Host: Jan Falguera
MSB 2170
Biochemistry George Connell Lecture seminars
Poster available: PDF icon Connell poster_TRAXLER.pdf

Wednesday, August 21, 2019 - 1:30pm

Investigating the roles of anionic phospholipids in endocytic trafficking in mammalian and S. cerevisiae cells
Yanbo Yang
Wednesday, August 21, 2019 - 1:30pm
Supervisor: Dr. Gregory Fairn
MSB 4171
Department of Biochemistry Seminar
PhD Exam Seminar
Poster available: PDF icon Ph.D.Poster.Yanbo_.Yang_.pdf

Wednesday, July 31, 2019 - 1:00pm

Structural characterization of prion protein misfolding using proteins from resistant species and antibodies
Ondrej Halgas
Wednesday, July 31, 2019 - 1:00pm
Supervisor: Dr. Emil Pai
MSB 3278
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Ondrej.Halgas.pdf

Wednesday, July 3, 2019 - 9:00am

Anti-CRISPRs and CRISPR-Cas: Characterization and biotechnology
Marios Mejdani
Wednesday, July 3, 2019 - 9:00am
Supervisor: Dr. Alan Davidson
MSB 2173
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.MariosMejdani.pdf

Wednesday, May 29, 2019 - 2:00pm

Cell-Wall Recycling in Pseudomonas aeruginosa and the Nexus to Antibiotic Resistance
Prof. Shahriar Mobashery
Navari Family Professor in Life Sciences, Department of Chemistry & Biochemistry, University of Notre Dame
Wednesday, May 29, 2019 - 2:00pm
MSB 2172
Department of Biochemistry Seminar
Special Seminar
Poster available: PDF icon Poster_Shahriar Mobashery.pdf

Wednesday, May 29, 2019 - 9:00am

Discovery of novel antibiotics via Streptomyces sporulation
Scott McAuley
Wednesday, May 29, 2019 - 9:00am
Supervisor: Dr. Justin Nodwell
Medical Sciences Building, Room 3278
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Scott_.McAuley.pdf

Friday, May 24, 2019 - 2:00pm

Integrated Experimental and Bioinformatics Approach to Investigate Metabolic Channelling
Kris Hon
Friday, May 24, 2019 - 2:00pm
Supervisor: Dr. John Parkinson
MSB 2173
Department of Biochemistry Seminar
PhD Exam Seminar
Poster available: PDF icon Ph.D.Poster.Kris_.Hon_.pdf

Wednesday, May 22, 2019 - 4:00pm

Identifying inhibitors of Slam-dependent SLP translocation
Esther Shin
PhD Student
Wednesday, May 22, 2019 - 4:00pm
Supervisor: Dr. Trevor Moraes, Committee Members: Dr. Roman Melnyk and Dr. Alex Ensminger
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series
Structural features of GPCR and G-protein activation investigated with 19F NMR
Alexander P. Orazietti
PhD Student
Wednesday, May 22, 2019 - 4:00pm
Supervisor: Dr. R. Scott Prosser, Committee Members: Dr. Oliver Ernst, Dr. Trevor Moraes
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series

Tuesday, May 21, 2019 - 4:00pm

Probing neurodegeneration with genome wide perturbations and 3D histology
DR. ADRIANO AGUZZI
University of Zurich, Institute of Neuropathology, Zurich, Switzerland
Tuesday, May 21, 2019 - 4:00pm
Host: Dr. Igor Stagljar
CCBR Red Room
Department of Biochemistry George Connell Lecture
Poster available: PDF icon Connell 2019_Adriano Aguzzi.pdf

Wednesday, May 15, 2019 - 4:00pm

Peptide-based inhibition of the Small Multidrug Resistant protein in antibiotic resistant bacteria
Chloe Mitchell
PhD Student
Wednesday, May 15, 2019 - 4:00pm
Supervisor: Dr. Charles Deber, Committee Members: Dr. Roman Melnyk and Dr. Reinhart Reithmeier
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series
Novel Phage Tail-Like Bacterial Structures and Their Role in Streptomyces
Maria Vladimirov
PhD Student
Wednesday, May 15, 2019 - 4:00pm
Supervisor: Dr. Alan Davidson, Committee Members: Dr. Justin Nodwell, Dr. Scott Gray-Owen
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series

Wednesday, May 8, 2019 - 4:00pm

The RavA-ViaA Complex Interacts with and Modulates the Activity of the Fumarate Reductase Respiratory Complex
Vaibhav Bhandari
PhD Student
Wednesday, May 8, 2019 - 4:00pm
Supervisor: Dr. Walid A. Houry, Committee Members: Dr. Trevor F. Moraes, Dr. Roman Melnyk
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series
Discovery of a novel naturally produced host-targeted anti-virulence compound
Simoun Icho
PhD Student
Wednesday, May 8, 2019 - 4:00pm
Supervisor: Dr. Roman Melynk, Committee Members: Dr. Justin Nodwell and Dr. Jean-Philippe Julien
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series

Wednesday, May 1, 2019 - 4:00pm

In Silico screening using IBM Watson to identify novel small molecule enhancers of mitophagy
Natalia Moskal
PhD Student
Wednesday, May 1, 2019 - 4:00pm
Supervisor: Dr. Angus McQuibban, Committee Members: Dr. Roman Melnyk, Dr. Joanne Nash
MSB 2172
Department of Biochemistry, Graduate Student Seminar Series

Thursday, April 25, 2019 - 2:00pm

Investigation of the immunogenicity and specificity of the Transferrin binding proteins from bovine pathogenic bacteria
Anastassia Pogoutse
Thursday, April 25, 2019 - 2:00pm
Supervisor: Dr. Trevor Moraes
CCBR, Black Room
Department of Biochemistry Seminar
PhD Oral Seminar
Poster available: PDF icon Ph.D.Poster.Ana_.Pogoutse.pdf

Wednesday, April 24, 2019 - 4:00pm

PROTEIN TRANSPORT ACROSS MEMBRANES
DR. Tom Rapoport
Professor of Cell Biology and HHMI Investigator, HHMI/Harvard Medical School
Wednesday, April 24, 2019 - 4:00pm
Host: Kathleen Orrell
MSB 2172
Department of Biochemistry George Connell Lecture
Poster available: PDF icon Connell 2019_Tom Rapoport.pdf

Wednesday, April 17, 2019 - 4:00pm

Getting excited about NMR, structure, mechanisms, the unknown and curing cancer
Dr. Gerhard Wagner
Elkan R. Blout Professor, Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School
Wednesday, April 17, 2019 - 4:00pm
Host: Alexander Orazietti
MSB 2172
Department of Biochemistry George Connell Lecture
Poster available: PDF icon Connell 2019_Gerhard Wagner.pdf

Wednesday, April 17, 2019 - 9:00am

Chaperone Systems in Model Organisms
Kamran Rizzolo
Wednesday, April 17, 2019 - 9:00am
Supervisor: Dr. Walid Houry
MSB 2173
Department of Biochemistry Seminar
PhD Exam Seminar
Poster available: PDF icon Ph.D.Poster.Kamran.Rizzolo.pdf

Wednesday, April 10, 2019 - 4:00pm

Transmission of misfolded proteins in neurodegenerative disorders – a common mechanism of disease progression
DR. VIRGINIA M.-Y. LEE
Professor, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Director, Center for Neurodegenerative Disease Research
Wednesday, April 10, 2019 - 4:00pm
Host: Raphaella So
MSB 2172
Department of Biochemistry George Connell Lecture
Poster available: PDF icon Connell 2019_Virginia M.Y. Lee.pdf

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