Previous Seminars

Thursday, April 20, 2023 - 12:00pm

"AAV-based gene therapy approaches for treating monogenic lung diseases" Dr. Sarah Wootton Thursday, April 20, 2023 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Thursday, April 20, 2023 - 4:00pm

Copper depletion cancer therapy Dr. Jianghong Rao Professor, Department of Radiology, Lucas Imaging Center, Stanford University Thursday, April 20, 2023 - 4:00pm Host: Dr. Gang Zheng PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Invited Speaker Seminar

Friday, April 21, 2023 - 11:00am

CRISPR-based functional genomic tools and applications to understanding antifungal resistance and fungal virulence Rebecca Shapiro Department of Molecular and Cellular Biology, University of Guelph Friday, April 21, 2023 - 11:00am Host: Professor Shelley Lumba Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology Invited Speaker Seminar

Friday, April 21, 2023 - 1:00pm

What's new in Osteoarthritis? Emerging Technologies and Research Tools Sowmya Viswanathan, PhD Friday, April 21, 2023 - 1:00pm Host: Dr. Boris Hinz Li Ka Shing Auditorium, St. Michael's Hospital, 209 Victoria St. KRC Research Seminar Series Research Group Seminar

Monday, April 24, 2023 - 1:00pm

Nuclear Organization by Biomolecular Condensates BENJAMIN SABARI Assistant Professor Department of Molecular Biology UT Southwestern Medical Center Monday, April 24, 2023 - 1:00pm Host: JONATHON DITLEV PGCRL- 686 Bay St. (SickKids), Event Room 3A/3B (3rd Floor) OR Join on Zoom Molecular Medicine Seminar Series Invited Speaker Seminar Poster available: MM Seminar - Ben Sabari April 24.pdf

Tuesday, April 25, 2023 - 12:00pm

Strategies for Pharmacological modulation of mitophagy Natalia Moskal Tuesday, April 25, 2023 - 12:00pm Supervisor: Dr. Angus McQuibban; Supervisory Committee Members: Dr. Roman Melnyk & Dr. Joanne Nash Zoom PhD Oral Seminar

Wednesday, April 26, 2023 - 2:00pm

Structural Insights into Modification and Export of the Pseudomonas aeruginosa Alginate Exopolysaccharide Andreea Gheorghita Wednesday, April 26, 2023 - 2:00pm Supervisor: Dr. P. Lynne Howell; Supervisory committee members: Dr. Christine Bear & Dr. Trevor Moraes MSB 7231 PhD Exam Seminar

Friday, April 28, 2023 - 1:00pm

Understand and using immune cells to engineer cardiac tissues. Slava Epelman MD, PhD, FRCPC University Health Network / University of Toronto Friday, April 28, 2023 - 1:00pm Host: Dr. Boris Hinz Li Ka Shing Auditorium, St. Michael's Hospital, 209 Victoria St. Keenan Research Centre Research Seminar Series, St. Michael's Hospital Research Group Seminar

Friday, April 28, 2023 - 1:30pm

Transcytosis of Gut Antigens by Human M Cells Requires Coronin 1A Dr. Nicholas C. Zachos, PhD Department of Surgery, The Epithelial Biology Center, Vanderbilt University Medical Center Friday, April 28, 2023 - 1:30pm Host: Dr. Aleixo Muise PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Poster available: Zachos.pdf

Wednesday, May 3, 2023 - 12:00pm

Not alone: two examples of ion channels forming protein complexes to modulate cellular excitability Stephan Pless University of Copenhagen Wednesday, May 3, 2023 - 12:00pm Host: Dr. Mei Zhen Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 Lunenfeld-Tanenbaum Seminar Series Invited Speaker Seminar Poster available: Stephan Pless - Seminar Advertising May 3, 2023.pdf

Thursday, May 4, 2023 - 12:00pm

T cell Glycosylation in Health and Disease Landon J. Edgar Department of Pharmacology & Toxicology, Department of Chemistry, University of Toronto Thursday, May 4, 2023 - 12:00pm Host: Wilson Zeng McLennan Physical Laboratories, Room MP606 BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: Edgar_Landon_May4.pdf

"Blood-based Biomarkers of Disease Activity in CF" Dr. Brad Quan Thursday, May 4, 2023 - 12:00pm Virtual: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Thursday, May 4, 2023 - 4:00pm

Rewiring Cell Division Dr. Iain Cheeseman Professor, Whitehead Institute and Department of Biology, MIT Thursday, May 4, 2023 - 4:00pm Host: Dr. Shane Harding PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Invited Speaker Seminar

Friday, May 5, 2023 - 1:30pm

Nutrient remodeling of pancreatic islet beta-cell secretory capacity Samuel Stephens Department of Internal Medicine, Division of Endocrinology & Metabolism, University of Iowa Friday, May 5, 2023 - 1:30pm Host: Dr. Amira Klip PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Poster available: Stephens.pdf

Tuesday, May 9, 2023 - 11:00am

A Disease at the Crossroads: Developments for Huntington's Disease Therapeutic Strategies Jeffrey Carroll, PhD Associate Professor, Department of Neurology, University of Washington Tuesday, May 9, 2023 - 11:00am Host: Rachel Harding MSB 2170 Pharmacology and Toxicology Seminar Special Seminar Poster available: Carroll Poster[42] - Read-Only.pdf

Tuesday, May 9, 2023 - 2:00pm

The DNA Replication Stress Response to Gemcitabine in Pancreatic Cancer Cells Tajinder Ubhi Tuesday, May 9, 2023 - 2:00pm Supervisor: Dr. Grant Brown; Supervisory Committee Members: Dr. Stephane Angers & Dr. Daniel Durocher CCBR Red Room PhD Oral Seminar Poster available: Tajinder_Ubhi_Poster.pdf

Wednesday, May 10, 2023 - 12:00pm

High throughput functional annotation of pharmacogene variants using yeast activity assays Dr. Maitreya Dunham Professor of Genome Sciences, University of Washington Wednesday, May 10, 2023 - 12:00pm Host: Kate Jiang ((kate.jiang@mail.utoronto.ca) MSB 2172 Department of Biochemistry George Connell Lecture Invited Speaker Seminar Poster available: Connell poster_DUNHAM.pdf

Thursday, May 11, 2023 - 12:00pm

"Polymicrobial interactions and antimicrobial susceptibility in CF" Dr. Valerie Waters Thursday, May 11, 2023 - 12:00pm PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Cystic Fibrosis Seminar

Thursday, May 11, 2023 - 4:00pm

Direct cytosolic delivery of biologics using polymer vectors: anti-inflammatory and anti-cancer therapeutics Dr. Vince Rotello Distinguished Professor, University of Massachusetts Thursday, May 11, 2023 - 4:00pm Host: Dr. Gang Zheng PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series

Friday, May 12, 2023 - 1:00pm

Skeletal muscle dysfunction in the critical illness survivor - determining mechanism Jane Batt, MD PhD Respirologist and Scientist at St. Michael’s Hospital, Unity Health Toronto. Associate Professor of Medicine, University of Toronto. Friday, May 12, 2023 - 1:00pm Host: Dr. Boris Hinz Li Ka Shing Auditorium, St. Michael's Hospital, 209 Victoria St. Keenan Research Centre Research Seminar Series, St. Michael's Hospital Research Group Seminar

Friday, May 12, 2023 - 1:30pm

Membrane-associated actin filaments: multi-scale determinants of cell shape and biomechanics Dr. Velia M. Fowler, PhD Professor and Chair, Department of Biological Sciences, University of Delaware Friday, May 12, 2023 - 1:30pm Host: Dr. Sergio Grinstein PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Poster available: Fowler.pdf

Wednesday, May 17, 2023 - 12:00pm

Information theory and signal processing for CFTR and other receptors Dr. Andrew Eckford Wednesday, May 17, 2023 - 12:00pm Host: Nevraj Kejiou (nevraj kejiou@mail.utoronto.ca) MSB 2172 Department of Biochemistry George Connell Lecture Departmental Seminar Poster available: Connell poster_ECKFORD.pdf

Thursday, May 18, 2023 - 12:00pm

Beyond the permeation-selectivity trade-off: Simultaneous optimization of discordant processes to achieve biomolecular function Michael P. Zwolak National Institute of Standards and Technology (NIST) Thursday, May 18, 2023 - 12:00pm Host: Wilson Zeng Zoom BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: Zwolak_Mike_May 18.pdf

“Genome-Wide Single Cell RNA-Sequencing Co-Expression Analysis with CFTR in Lung Tissue” Dr. Lisa Strug, Cheng Wang Thursday, May 18, 2023 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Friday, May 19, 2023 - 1:00pm

Atomic Force Microscopy: The Nexus Between Physics and Biology Luisa Ulloa Severino, PhD Unity Health Toronto, University of Toronto Friday, May 19, 2023 - 1:00pm Host: Dr. Darren Yuen Li Ka Shing Auditorium, St. Michael's Hospital, 209 Victoria St. Keenan Research Centre Research Seminar Series, St. Michael's Hospital Research Group Seminar

Friday, May 19, 2023 - 1:30pm

Neurodegenerative Disorders: From Molecular Mechanisms to Targeted Therapies Dr. Dimitri Krainc, MD/PhD Chair, Department of Neurology, Feinberg School of Medicine, Northwestern University Friday, May 19, 2023 - 1:30pm Host: Dr. John Brumell Via Zoom Program in Cell Biology Seminar Series  Poster available: Krainc.pdf

Friday, May 26, 2023 - 1:30pm

Using Pathogen-Guided Approaches to Discover Evolutionarily Conserved Antiviral Responses Dr. Don B. Gammon, PhD Assistant Professor, Department of Microbiology, UT Southwestern Medical Center Friday, May 26, 2023 - 1:30pm Host: Dr. John Brumell Via Zoom Program in Cell Biology Seminar Series  Poster available: Gammon.pdf

Thursday, June 1, 2023 - 4:00pm

Hematopoietic stem cell-intrinsic and -extrinsic contribution to aging and clonal hematopoiesis Jennifer Trowbridge, PhD Professor, The Dattels Family Chair, JAX Center for Aging Research, The JAX Cancer Center, The Jackson Laboratory, Bar Harbor, Maine, USA Thursday, June 1, 2023 - 4:00pm Host: Dr. Courtney Jones PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Invited Speaker Seminar

Friday, June 2, 2023 - 1:00pm

From Prion gene evolution through function to therapy: Targeting sodium-potassium pumps for the treatment of prion diseases and Alzheimer's disease" Professor Gerold Schmitt-Ulms, PhD University of Toronto Friday, June 2, 2023 - 1:00pm Host: Dr. Raphael Schneider Li Ka Shing Auditorium, St. Michael's Hospital, 209 Victoria St. KRC Research Seminar Series Research Group Seminar

Friday, June 2, 2023 - 1:30pm

From Tissues to Cells: Application of Various Modalities of Light Sheet Imaging Imaging Facility The Hospital for Sick Children, Research Institute Friday, June 2, 2023 - 1:30pm Host: Dr. Sergio Grinstein PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Poster available: Imaging talk.pdf

Monday, June 5, 2023 - 1:00pm

Exploring the dark matter of phage genomes and its role in antiviral defence KAREN MAXWELL Associate Professor, Department of Biochemistry University of Toronto Monday, June 5, 2023 - 1:00pm Host: DR. LYNNE HOWELL PGCRL- 686 Bay St. (SickKids), Event Room 3A/3B (3rd Floor) OR Join on Zoom Molecular Medicine Seminar Series Invited Speaker Seminar Poster available: MM Seminar - Karen Maxwell (June 5)[55].pdf

Tuesday, June 6, 2023 - 4:00pm

Fly Macrophages, Migration, and the Extracellular Matrix Brian Stramer, PhD Randall Centre for Cell and Molecular Biophysics, King's College London Tuesday, June 6, 2023 - 4:00pm Host: Professor Ashley Bruce Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology Special Seminar

Thursday, June 8, 2023 - 1:00pm

CFTR variant liability assignment and recent expansion of CFTR2 Dr. Johanna Rommens Thursday, June 8, 2023 - 1:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Friday, June 9, 2023 - 1:00pm

Engineering niches to uncover principles guiding skeletal muscle stem cell fate Penney M. Gilbert, PhD University of Toronto Friday, June 9, 2023 - 1:00pm Host: Dr. Boris Hinz Li Ka Shing Auditorium, St. Michael's Hospital, 209 Victoria St. KRC Research Seminar Series Research Group Seminar

Monday, June 12, 2023 - 1:00pm

What’s phage gut to do with it? Contrasting intestinal phage-bacteria interactions from early life to adulthood CORINNE MAURICE Canada Research Chair in Gut Microbial Physiology Associate Professor, Microbiology & Immunology Dept. McGill University Monday, June 12, 2023 - 1:00pm Host: JOHN PARKINSON PGCRL- 686 Bay St. (SickKids), Event Room 3A/3B (3rd Floor) OR Join on Zoom Molecular Medicine Seminar Series Poster available: MM Seminar - Corinne Maurice June 12.pdf

Thursday, June 15, 2023 - 12:00pm

The role of the microbiome in global health Zulfiqar Bhutta and John Parkinson Zulfiqar Bhutta (Co-Director, SickKids Centre for Global Child Health and Senior Scientist, Child Health Evaluative Sciences) and John Parkinson (Senior Scientist, Molecular Medicine) Thursday, June 15, 2023 - 12:00pm Through ZOOM Research Group Seminar Poster available: Research Connections_ June 15 2023.pdf

“Best of the West: Update on CF Research from BC Children’s Hospital” Dr. Jonathan Rayment Thursday, June 15, 2023 - 12:00pm Virtual: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Thursday, June 15, 2023 - 4:00pm

"DNA dynamics, topoisomerases and transcriptional amplification by MYC; a framework to understand MYC function and pathology" David Levens, MD, PhD Senior Investigator, Lab. of Pathology, Center for Cancer Research, National Cancer Institute Thursday, June 15, 2023 - 4:00pm Host: Dr. Linda Penn PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Invited Speaker Seminar

Friday, June 16, 2023 - 11:00am

Nutritional adaptation by fungal pathogens Jim Kronstad, Ph.D. Professor, The University of British Columbia, Michael Smith Laboratories Friday, June 16, 2023 - 11:00am Host: Professor Shelley Lumba Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology Special Seminar

Thursday, June 22, 2023 - 12:00pm

"Pulmonary MRI in Cystic Fibrosis" Dr. Brandon Zanette Thursday, June 22, 2023 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Thursday, June 22, 2023 - 4:00pm

Epigenomics in hormone-driven cancers: from trials to models and back again Dr. Wilbert Zwart The Netherlands Cancer Institute Thursday, June 22, 2023 - 4:00pm Host: Dr. Mathieu Lupien PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Invited Speaker Seminar Poster available: Seminar Notice_Wilbert Zwart_June 22, 2023.pdf

Friday, June 23, 2023 - 1:00pm

Utilizing omic technologies to understand the heterogeneity of osteoarthritis Professor Mohit Kapoor PhD Unity Health Network Friday, June 23, 2023 - 1:00pm Host: Dr. Andras Kapus Li Ka Shing Auditorium, St. Michael's Hospital, 209 Victoria St. KRC Research Seminar Series Research Group Seminar

Wednesday, June 28, 2023 - 11:00am

Using Drosophila to study injury- and disease-associated pain Professor Michael Galko University of Texas MD Anderson Cancer Center Wednesday, June 28, 2023 - 11:00am Host: Professor Rodrigo Fernandez-Gonzalez Ramsay Wright Building, Room 432 Dept of Cell and Systems Biology Special Seminar

Thursday, June 29, 2023 - 12:00pm

“New insights into antibiotic sensitivity and resistance in Gram positive pathogens” Dr. Justin Nodwell Thursday, June 29, 2023 - 12:00pm Virtual: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Thursday, June 29, 2023 - 4:00pm

"Development of a first clinically viable MYC inhibitor for cancer treatment" Laura Soucek, PhD Professor, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain Thursday, June 29, 2023 - 4:00pm Host: Dr. Linda Penn PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Invited Speaker Seminar

Friday, July 21, 2023 - 1:30pm

Tales from the Crypt: pinpointing how, when and where necroptosis contributes to IBD Dr. James Murphy, PhD Head, Inflammation Division and Andre Samson, PhD, Senior Research Officer, Inflammation Division Walter & Eliza Hall Institute of Medical Research Friday, July 21, 2023 - 1:30pm PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Murphy_Samson.pdf

Tuesday, August 15, 2023 - 9:00am

Cellular Trash Talk: Exploring the Limits of Autophagy in Health and Disease. Kyla Germain Tuesday, August 15, 2023 - 9:00am Supervisor: Dr. Peter Kim; CoSupervisor: Dr. Robert Bandsma / Supervisory committee members: Dr. Walter Kahr & Dr. John Brumell PGCRL, Event Room 1 PhD Oral Seminar

Tuesday, August 15, 2023 - 1:00pm

Salmonella Typhimurium evades degradation through suppression of ER autophagy receptors Dr. Ryan Russell, PhD Associate Professor & Director, Genome Editing and Molecular Biology, Cellular and Molecular Medicine, Medicine, University of Ottawa Tuesday, August 15, 2023 - 1:00pm Host: Dr. Peter Kim PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Russell.pdf

Tuesday, August 15, 2023 - 3:00pm

Finding new ligands to the SARS CoV2 Macrodomain using Fragments, Neurons and Entropy Dr. James Fraser, Ph.D. Professor, Dept. of Bioengineering and Therapeutic Sciences, University of California San Francisco Tuesday, August 15, 2023 - 3:00pm Host: Department of Pharmacology and Toxicology MSB 4171 Pharmacology and Toxicology Seminar Special Seminar Poster available: Fraser Poster.pdf

Tuesday, August 22, 2023 - 9:00am

Investigations into the Phage-Host Dynamics of Streptomyces Sarah Kronheim Tuesday, August 22, 2023 - 9:00am Supervisor: Dr. Karen Maxwell; Supervisory committee members: Dr. Justin Nodwell & Dr. Roman Melnyk Medical Sciences Building, Room 3278 PhD Oral Seminar