Previous Seminars

Monday, December 3, 2018 - 11:00am

Monday, December 3, 2018 - 4:00pm

The Importance of Cell Type - Molecular Mechanisms of Circuit Modulation in the Mammalian Brain Dr. Nathaniel Heintz Rockefeller University Monday, December 3, 2018 - 4:00pm Host: Dr. James Ellis MSB 2172 Department of Molecular Genetics Invited Speaker Seminar Poster available: Heintz Poster.pdf

Wednesday, December 5, 2018 - 1:30pm

A solid state conceptualization of information transfer from gene to message to protein DR. STEVEN McKNIGHT Professor, Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX Wednesday, December 5, 2018 - 1:30pm Host: Brian Tsang PG CRL Auditorium, 686 Bay St., SickKids Department of Biochemistry George Connell Lecture Poster available: Connell 2018_Steven McKnight.pdf

Wednesday, December 5, 2018 - 4:00pm

Thursday, December 6, 2018 - 11:00am

Therapeutic targeting of stem cell self-renewal in childhood medulloblastoma: Strategies for blocking recurrence Sheila K. Singh, MD, PhD, FRCS(C) Senior Canada Research Chair in Human Cancer Stem Cell Biology | Pediatric Neurosurgeon, McMaster Children's Hospital | Professor of Surgery, McMaster University | Principal Investigator, Stem Cell and Cancer Research Institute, McMaster University | Director, McMaster Surgeon Scientist Program | Chief Executive Officer, Empirical Therapeutics Thursday, December 6, 2018 - 11:00am Host: Jason Moffat, PhD | Professor, The Donnelly Centre, Department of Molecular Genetics, University of Toronto CCBR Red Room Donnelly Seminar Series Invited Speaker Seminar Co-sponsor: Donnelly Seminar Series Poster available: Sheila Singh donnelly poster.pdf

Therapeutic targeting of stem cell self-renewal in childhood medulloblastoma: Strategies for blocking recurrence Sheila K. Singh, MD, PhD, FRCS(C) Pediatric Neurosurgeon, McMaster Children's Hospital | Interim Division Head, Neurosurgery, Hamilton Health Sciences | Director, McMaster Surgeon Scientist Program | Professor of Surgery, McMaster University | PI, Stem Cell and Cancer Research Institute, McMaster University | Canada Research Chair in Human Cancer Stem Cell Biology Thursday, December 6, 2018 - 11:00am Host: Jason Moffat, PhD | Professor, The Donnelly Centre, Department of Molecular Genetics, University of Toronto CCBR Red Room Donnelly Seminar Series Invited Speaker Seminar Poster available: Sheila Singh donnelly poster.pdf

Thursday, December 6, 2018 - 4:00pm

Friday, December 7, 2018 - 11:00am

Friday, December 7, 2018 - 1:30pm

Phosphoinositide signaling in phagosome formation, maturation and resolution Dr. Sergio Grinstein, PhD Cell Biology Program, The Hospital for Sick Children Friday, December 7, 2018 - 1:30pm PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Grinstein.pdf

Monday, December 10, 2018 - 3:00pm

Monday, December 10, 2018 - 4:00pm

Unmasking transposable elements Dr. Guillaume Bourque McGill University Monday, December 10, 2018 - 4:00pm Host: Dr. Quaid Morris MSB 2172 Department of Molecular Genetics Invited Speaker Seminar Poster available: Bourque poster.pdf

Developing inhibitors for CRISPR-Cas9 genome editing Karen Maxwell, PhD Assistant Professor, Department of Biochemistry, University of Toronto Monday, December 10, 2018 - 4:00pm Host: Jeffrey Lee, PhD MSB 2170 Laboratory Medicine and Pathobiology Seminar Departmental Seminar Poster available: Poster KMaxwell.pdf

Tuesday, December 11, 2018 - 10:00am

Protein-Protein and Protein-DNA Interactions Of The Human C2H2 Zinc Finger Proteins Ernest Radovani Tuesday, December 11, 2018 - 10:00am Supervisor: Drs. Jack Greenblatt and Timothy Hughes MSB 4171 Department of Molecular Genetics PhD Exam Seminar Poster available: Radovani poster.pdf

Tuesday, December 11, 2018 - 1:30pm

Tuesday, December 11, 2018 - 3:00pm

Forty years of TF motifs: Lessons and Challenges Dr. Gary D. Stormo Washington University Tuesday, December 11, 2018 - 3:00pm Host: Drs. Jack Greenblatt and Timothy Hughes CCBR Red Room Department of Molecular Genetics Invited Speaker Seminar Poster available: Stormo poster.pdf

Wednesday, December 12, 2018 - 9:30am

mitoCPR- a stress response that maintains mitochondria homeostasis Dr. Hilla Weidberg Massachusetta Institute of Technology, Cambridge, MA, USA Wednesday, December 12, 2018 - 9:30am Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Hilla Weidberg.pdf

Wednesday, December 12, 2018 - 12:00pm

Wednesday, December 12, 2018 - 4:00pm

Thursday, December 13, 2018 - 4:00am

Thursday, December 13, 2018 - 10:00am

Origina and Diversification of the deubiquitinating enzyme Dr. Doug Gray University of Ottawa Thursday, December 13, 2018 - 10:00am Host: Dr. Lori Frappier MSB 3278 Department of Molecular Genetics Invited Speaker Seminar Poster available: Gray poster.pdf

Thursday, December 13, 2018 - 1:00pm

Interactions And Functions Of The Ubiquitin Specific Protease 7 Anna-Marie Georges Thursday, December 13, 2018 - 1:00pm Supervisor: Dr. Loori Frappier MSB 4171 Department of Molecular Genetics PhD Exam Seminar Poster available: Georges poster.pdf

Thursday, December 13, 2018 - 4:00pm

New chemoenzymatic tools for spatially-resolved mapping of post-translational modifications in living cells Dr. Amy Weeks University of California - San Francisco, CA, USA Thursday, December 13, 2018 - 4:00pm Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-300 LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Amy Weeks.pdf

Friday, December 14, 2018 - 1:30pm

From single-cells to patient diagnosis: statistical machine learning approaches to biomedical discovery Dr. Kieran Campbell Department of Statistics, University of British Columbia; Department of Molecular Oncology, BC Cancer Agency Friday, December 14, 2018 - 1:30pm Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Kieran Campbell.pdf

Friday, December 14, 2018 - 4:00pm

The role of Mkrn2 in mRNA nuclear export Eric Wolf University of Toronto, Department of Molecular Genetics Friday, December 14, 2018 - 4:00pm Host: Toronto RNA Club Supervisor: Dr. Andrew Emilli CCBR Red Room Toronto RNA Club Poster available: toronto-rna-club-december 2018.pdf

Friday, December 14, 2018 - 4:30pm

Systematic analysis of alternative polyadenylation from RNA-seq data Kevin Ha University of Toronto, Department of Molecular Genetics Friday, December 14, 2018 - 4:30pm Host: Toronto RNA Club Supervisor: Dr. Quaid Morris & Dr. Ben Blencowe CCBR Red Room Toronto RNA Club Poster available: toronto-rna-club-december 2018.pdf

Monday, December 17, 2018 - 2:00pm

Characterization of CEACAM1 spatial distribution, self-association and dynamics using high-resolution microscopy techniques Amine Driouchi Monday, December 17, 2018 - 2:00pm Supervisor: Dr. Christopher Yip MSB 2173 Department of Biochemistry Seminar PhD Oral Seminar Poster available: Ph.D.Poster.Aminie.Driouchi.pdf

Tuesday, December 18, 2018 - 3:00pm

Transmission of non-genetic information by sperm small RNAs Dr. Colin C. Conine Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School Tuesday, December 18, 2018 - 3:00pm PMH, 610 University Avenue, 7th Floor, Rm 7-605 LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Colin Coline.pdf

Wednesday, December 19, 2018 - 4:00pm

Thursday, December 20, 2018 - 9:00am

Clonal Heterogeneity and Evolution in Primary Tumors and Metastases Ben Raphael Department of Computer Science, Princeton University Thursday, December 20, 2018 - 9:00am Host: Drs. Quaid Morris and Michael Hoffman MaRS- TMDT R# 4-204, 4th floor Special Seminar Poster available: Seminar Notice for Posting- Dr. Ben Raphael.pdf

Thursday, December 20, 2018 - 10:30am

Data science and infectious disease: from outbreaks to antimicrobial resistance Dr. Robyn S. Lee Department of Epidemiology Center for Communicable Disease Dynamics, Harvard T.H Chan School of Public Health Thursday, December 20, 2018 - 10:30am MSH- 60 Murray St. - Level 3 Cooper Centre LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Robyn Lee.pdf

Monday, January 7, 2019 - 1:00pm

The 'Complex' Problem of Purine Metabolism Jarrod French, PhD Assistant Professor, Department of Chemistry, Department of Biochemistry and Cell Biology, Stony Brook University Monday, January 7, 2019 - 1:00pm Host: SickKids Faculty Recruitment Seminar - Biological Assembly & Phase Separation Position PGCRL Event Rooms 2A/2B (02.9310, 2nd Floor) Faculty Recruitment Seminar Faculty Recruitment Seminar Poster available: Recruitment Seminar - French.pdf

Tuesday, January 8, 2019 - 1:00pm

The single cell pathology landscape of breast cancer: tumour cells and their microenvironments Dr. Hartland Jackson University of Zurich Tuesday, January 8, 2019 - 1:00pm Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Hartland Jackson.pdf

Wednesday, January 9, 2019 - 2:00pm

Determinants of Drug Preference: Translational Studies Harriet de Wit, Ph.D. Professor, Department of Psychiatry and Behavioral Neuroscience, University of Chicago Wednesday, January 9, 2019 - 2:00pm Host: Dr. Rachel Tyndale, Department of Pharmacology & Toxicology HartHouse, Great Hall, University of Toronto, 7 Hart House Circle Pharmacology & Toxicology “Distinguished Lecture in Behavioural Pharmacology” Poster available: Dr Harriet de Wit.pdf

"Principles of Epigenetics and Chromatin in Development and Human Disease" Ali Shilatifard, PhD Chairman, Department of Biochemistry and Molecular Genetics Director, Simpson Querrey Center for Epigenetics, Robert Francis Furchgott Professor Biochemistry and Pediatrics, Northwestern University Feinberg School of Medicine Wednesday, January 9, 2019 - 2:00pm Host: Cheryl Arrowsmith PhD MaRS- TMDT R# 4-204, 4th floor SGC Seminar Invited Speaker Seminar

Wednesday, January 9, 2019 - 4:00pm

Thursday, January 10, 2019 - 9:00am

Metabolic dysfunction and human disease phenotypes Ralph J. DeBerardinis, MD, PhD Profressor, Children's Medical Centre Research Institute (CRI), University of Texas Southwestern Medical Centre Thursday, January 10, 2019 - 9:00am Host: Neal Sondheimer, MD, PhD Hospital for Sick Children, 555 University Avenue, Room 1246 Black Wing Genetics & Genome Biology Program Poster available: DeBerardinis_2019Jan10.pdf

Thursday, January 10, 2019 - 1:00pm

Deciphering cis-regulatory logic to understand disease-associated regulatory variation Dr. Carl de Boer Broad Institute Cambridge, MA, USA Thursday, January 10, 2019 - 1:00pm Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms, L3-201-202-203 LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Carl de Boer.pdf

Thursday, January 10, 2019 - 4:00pm

Friday, January 11, 2019 - 10:00am

Innate immune defense against intracellular pathogens: lessons learned from Legionella pneumophila Sunny Shin, PhD Sunny Shin, PhD Associate Professor in Microbiology, University of Pennsylvania Perelman School of Medicine Friday, January 11, 2019 - 10:00am Host: Stephen Girardin, PhD MSB 7231 Laboratory Medicine and Pathobiology Seminar Special Seminar Poster available: Special Seminar.pdf

Friday, January 11, 2019 - 11:00am

Friday, January 11, 2019 - 12:00pm

Identifying Vulnerabilities Fungal Pathogens Through Functional and Chemical Genomic Analysis Dr. Leah E. Cowen, Ph.D. Department of Molecular Genetics, University of Toronto Friday, January 11, 2019 - 12:00pm Host: Neal Sondheimer PG CRL Auditorium, 686 Bay St., SickKids Invited Speaker Seminar Poster available: 2019Jan11_LeahCowen.pdf

Friday, January 11, 2019 - 1:30pm

How cells control protein aggregation under stress. Dr. Hyun Kate Lee, PhD Department of Biochemistry, University of Toronto Friday, January 11, 2019 - 1:30pm Host: Dr. Peter K. Kim PG CRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Lee.pdf

Friday, January 11, 2019 - 4:00pm

PRMTs as Regulators of Post-Transcriptional Processes: Implications for Neuromuscular Disease and Cancer Dr. Jocelyn Côté University of Ottawa Friday, January 11, 2019 - 4:00pm Host: Toronto RNA Club CCBR Red Room Toronto RNA Club Poster available: TorontoRNAClubPoster2018-Jan12.pdf

Monday, January 14, 2019 - 9:30am

Caught between pathogens and autoimmunity: the evolution of our immune system Dr. Tzachi Hagai Wellcome Sanger Institute & European Bioinformatics Institute Cambridge, UK Monday, January 14, 2019 - 9:30am PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Tzachi Hagai.pdf

Monday, January 14, 2019 - 12:00pm

The queuine micronutrient pathway as a therapeutic target in autoimmune disease Vincent P. Kelly Assoc.Prof.School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Dublin, Ireland Monday, January 14, 2019 - 12:00pm Host: Colin McKerlie PG CRL Rm 2a, 2nd Fl, 686 Bay St., SickKids Translational Medicine Seminar Special Seminar Poster available: TMInvitedSpeakerKelly14012019.pdf

Monday, January 14, 2019 - 4:00pm

Investigating the architecture and function of key modules of the Autophagy machinery Calvin Yip, PhD Associate Professor, Department of Biochemistry and Molecular Biology, University of British Columbia. Monday, January 14, 2019 - 4:00pm Host: Jeffrey Lee, PhD MSB 2170 Laboratory Medicine and Pathobiology Seminar Departmental Seminar Poster available: Poster CY.pdf

Tuesday, January 15, 2019 - 10:00am

Genomic and "Big Data" approaches to neuropsychiatric phenotypes Dr. Jessica Dennis Vanderbilt University Medical Center Tuesday, January 15, 2019 - 10:00am Mount Sinai Hospital, 60 Murray St. Level 3 Cooper Centre LTRI-Principal Investigator Candidate Seminars Departmental Search Candidate Poster available: Jessica Dennis.pdf