A link between stress and restorative sleep

Professor William Wisden
Imperial College London
Friday, March 10, 2023 - 11:00am
Ramsay Wright Building, Room 432
Invited Speaker Seminar
In this talk, Wisden will present the lab’s findings that certain types of stress can induce a restorative sleep. This is mediated by sleep-inducing circuitry in the midbrain, and in particular, inhibitory GABA neurons in the ventral tegmental area. A specific circuit allows animals to restore mental and body functions by sleeping, potentially providing a refined route for treating anxiety disorders. Wisden will also present new (unpublished) findings on basal ganglia circuitry that generates REM sleep and how this REM circuitry can modulate anxiety.
Professor John Peever
Dept of Cell and Systems Biology
Live Stream Link: https://csb.utoronto.ca/live-stream/