Interfacing biologics design and chemical biology

Shohei Koide
Professor of Biologics Design,Perlmutter Cancer Center and Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine
Friday, June 7, 2019 - 3:00pm
Davenport Seminar Room, Chemistry Department, 80 St. George St.
Invited Speaker Seminar
Abstract: 
Biologics, such as engineered binding proteins, are rapidly transforming molecular medicine. We now have knowledge and technologies that enable rapid creation of biologics with high potency and exquisite selectivity. I will present our effort to expand the utility of biologics design in chemical biology, including new approaches to controlling conventionally undruggable targets such as RAS and to altering the substrate specificity of industrial enzymes.
Host: 
Andrew Woolley andrew.woolley@utoronto.ca