Epigenetic stability and dynamics during plant development

Professor Mary Gehring
Whitehead Institute
Friday, January 12, 2018 - 2:00pm
Ramsay Wright Building, Room 432
Invited Speaker Seminar
Cytosine DNA methylation is a heritable epigenetic mark important for transposable element silencing, genomic imprinting, and suppression of recombination. DNA methylation patterns are faithfully inherited between generations in plants. I will discuss the role of various genomic features in maintaining this stability and demonstrate that stable transgenerational methylation inheritance relies on a simple DNA-methylation sensing genetic circuit. I will also discuss the scope and consequences of epigenomic reprogramming during reproductive development, with a particular focus on small RNAs.
Professor John Calarco
Dept of Cell and Systems Biology