Mechanical ventilation optimization using transpulmonary pressure: Let’s not ignore overdistension

Objectives: 1. Understand chest wall physiology and the differences between transpulmonary pressure, trans-chest wall pressure and respiratory system pressures 2. Describe the relationship between pleural pressure and lung collapse 3. Explore the clinical history of esophageal manometry use in clinical care 4. Understand the importance of integrating markers of overdistension