"Cell Morphogenesis during Cell Division"

My laboratory studies molecular networks that regulate cell shape transformations during mitosis. ERM proteins (Ezrin, Radixin, Moesin) anchor actin filaments to the plasma membrane and bind microtubules at the cell cortex. By acting at the interface of the plasma membrane, the actin cytoskeleton and microtubules, ERM proteins are key players in the control of cell morphogenesis. I will present some of our latest discoveries on the role of the interplay between ERM, phosphoinositides and intracellular trafficking for cell shape transformations during cell division.