Previous Seminars

Thursday, April 7, 2022 - 12:00pm

Identifying critical steps in the ribosome assembly process using cryo-EM Dr. Joaquin Ortega Department of Anatomy and Cell Biology Centre for Structural Biology McGill University Thursday, April 7, 2022 - 12:00pm Host: Dr. Walid A. Houry Virtual Seminar BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: Joaquin Ortega_April 7_2022.pdf

"Mammalian Synthetic Biology: Foundation and Therapeutic Applications" Dr. Ron Weiss Thursday, April 7, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Zoom link Cystic Fibrosis Seminar

Thursday, April 7, 2022 - 2:00pm

Dynamic ER-PM contact sites and their impact on lipid homeostasis and phosphotyrosine signaling Minhyoung Lee Thursday, April 7, 2022 - 2:00pm Supervisor: Dr. Gregory Fairn Remote exam PhD Oral Seminar

Wednesday, April 20, 2022 - 9:00am

Remodeling of peptidoglycan biosynthesis in Staphylococcus aureus for enhanced antimicrobial activity and novel drug discovery Stephanie Tan Wednesday, April 20, 2022 - 9:00am Supervisor: Dr. Justin Nodwell Online PhD Exam Seminar

Thursday, April 21, 2022 - 12:00pm

Randomness, Complexity, and the Biological Frontier Dr. Pankaj Mehta Department of Physics Boston University Thursday, April 21, 2022 - 12:00pm Host: Jeremy Rothschild Virtual Seminar BiophysTO Lunchtime Talks Invited Speaker Seminar Poster available: PMehta_April21.pdf

Friday, April 22, 2022 - 1:30pm

Yes! Bacteria have organelles! How are they organized? Dr. Anthony G. Vecchiarelli, PhD Molecular, Cellular, and Developmental Biology, University of Michigan Friday, April 22, 2022 - 1:30pm Host: Dr. Julie Brill Via Zoom Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Vecchiarelli.pdf

Thursday, April 28, 2022 - 12:00pm

Early Pseudomonas aeruginosa infection and polymicrobial interactions in CF Dr. Valerie Waters Thursday, April 28, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Friday, April 29, 2022 - 12:00pm

Development of N-of-1 RNA Therapies in the Netherlands and Europe Dr. Willeke M.C. van Roon-Mom Department of Human Genetics, Leiden University Medical Center, The Netherlands Friday, April 29, 2022 - 12:00pm Host: Dr. Gregory Costain Zoom Leading Strand Series Poster available: Willeke M.C. van Roon-Mom Poster.pdf

Friday, April 29, 2022 - 1:30pm

Unlocking persisters to clear the infection Dr. Sophie Helaine, PhD Department of Microbiology, Harvard Medical School Friday, April 29, 2022 - 1:30pm Host: Dr. John Brumell Via Zoom Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Helaine.pdf

Thursday, May 5, 2022 - 12:00pm

Challenges and Progresses in developing next generation lung gene therapy for cystic fibrosis Dr. Jim Hu Thursday, May 5, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Friday, May 6, 2022 - 1:30pm

Dendritic cell migration at various scales Dr. Ana-Maria Lennon-Dumenil, PhD Director, Immunity and Cancer Department, Institut Curie Friday, May 6, 2022 - 1:30pm Host: Dr. Sergio Grinstein Via Zoom Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Lennnon-Dumenil.pdf

Tuesday, May 10, 2022 - 3:00pm

Tie2 and the host vascular response to severe infection Samir M. Parikh, MD University of Texas Southwestern Medical School Tuesday, May 10, 2022 - 3:00pm Host: Dr. Warren Lee Virtual Interdepartmental Division of Critical Care Medicine’s Visiting Professor Series Invited Speaker Seminar Poster available: IDCCM Visiting Professor Round on May 10, 2022 (1).pdf

Wednesday, May 11, 2022 - 4:00pm

CRISPR - A Revolutionary Tool for the Treatment of Blood Diseases Dr. Isaac Odame: Life with Thalassemia and Sickle , Dr. Zhenya Ivakine: The Marvelous Technology of CR, Dr. Donna Wall: First use of CRISPR Technology to The Hospital for Sick Children Wednesday, May 11, 2022 - 4:00pm Host: Garron Family Cancer Centre Via Zoom Translational Cancer Research Seminar Series Invited Speaker Seminar Poster available: Translational Seminar CRISPR[6].pdf

Thursday, May 12, 2022 - 12:00pm

Sputum inflammatory biomarkers to monitor CF lung disease Dr, Elad Ben-Meir Thursday, May 12, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Friday, May 13, 2022 - 1:30pm

Peroxisomes grease the wheel of the immune system Dr. Francesca Di Cara, PhD Department of Microbiology and Immunology, Dalhousie University Friday, May 13, 2022 - 1:30pm Host: Dr. Peter Kim Via Zoom Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Di Cara.pdf

Thursday, May 19, 2022 - 12:00pm

"High Quality Phased Whole Genome Sequence Across​ Cohorts is Achievable and Informs Phenotypic Variation in Cystic Fibrosis" and "A Cystic Fibrosis Lung Disease Modifier Locus Harbors Tandem Repeats Associated with Gene Expression" Dr. Lisa Strug, Scott Mastromatteo, Delnaz Roshandel Thursday, May 19, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Friday, May 20, 2022 - 1:30pm

The role of claudins in regulating calcium homeostasis Dr. Robert Todd Alexander, MD/PhD Department of Paediatrics, Division of Paediatric Nephrology, Faculty of Medicine & Dentistry, University of Alberta Friday, May 20, 2022 - 1:30pm Host: Dr. Mathieu Lemaire Via Zoom Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Alexander.pdf

Wednesday, May 25, 2022 - 10:00am

Epigenetic regulation of skin stem cells Dr. Elena Ezhkova Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York Wednesday, May 25, 2022 - 10:00am Host: Dr. Ian Scott, Collaborative Specialization in Developmental Biology Virtual Invited Speaker Seminar Poster available: Elena Ezhkova seminar May 25 2022.pdf

Friday, May 27, 2022 - 12:00pm

Functional variation in the human genome: lessons from the transcriptome Tuuli Lappalainen, PhD Professor, KTH Royal Institute of Technology Director, National Genomics Infrastructure & Genomics Platform, SciLifeLab Associate Faculty Member, New York Genome Center New York, USA Friday, May 27, 2022 - 12:00pm Host: Dr. Monica Justice Zoom - Register in advance for this webinar Poster available: Tuuli Lappalainen Poster .pdf

Thursday, June 2, 2022 - 2:00pm

Investigating the Biological Mechanisms Underlying Axis Morphogenesis Using a Novel Zebrafish Model of Idiopathic-like Scoliosis Chloe Rose Molecular Genetics Thursday, June 2, 2022 - 2:00pm Supervisor: Dr. Brian Ciruna MSB 4171 Department of Molecular Genetics PhD Oral Seminar

Friday, June 3, 2022 - 9:00am

Investigation of non-specific DNA binding by the type I-F CRISPR-Cas complex when bound to anti-CRISPR AcrIF9 Wang-Ting (Eric) Lu Friday, June 3, 2022 - 9:00am Supervisor: Dr. Alan Davidson; Supervisory Committee members: Dr. Trevor Moraes, Dr. Karen Maxwell Zoom online PhD Oral Seminar

Wednesday, June 8, 2022 - 9:00am

PEX13 is a novel regulator of peroxisome quality control Nicholas Demers Wednesday, June 8, 2022 - 9:00am Supervisor: Dr. Peter Kim; Supervisory Committee Members: Dr. Daniela Rotin, Dr. John Brumell Online PhD Oral Seminar

Thursday, June 16, 2022 - 12:00pm

“Functional MRI of Pediatric CF Lung Disease” Dr. Giles Santyr Thursday, June 16, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Friday, June 17, 2022 - 1:00pm

Leveraging High-Throughput Proteomics to Elucidate the Complex Pathogenic Program of Legionella pneumophila Harley Mount Friday, June 17, 2022 - 1:00pm Supervisor: Dr. Alex Ensminger Contact Ab Atre (studentservices.mogen@utoronto.ca) for Zoom Link Department of Molecular Genetics PhD Oral Seminar

Monday, June 20, 2022 - 9:00am

Elucidating Met receptor tyrosine kinase interactome to identify novel regulators of Met biology Shivanthy Pathmanathan Monday, June 20, 2022 - 9:00am Supervisor: Dr. Igor Stagljar Contact Ab Atre (studentservices.mogen@utoronto.ca) for Zoom Link Department of Molecular Genetics PhD Oral Seminar

Monday, June 20, 2022 - 1:00pm

Investigating Regulation of Cyclin-Dependent Kinases by SCF Ubiquitin Ligases and Pharmacological Kinase Inhibitors Susan Kelso Monday, June 20, 2022 - 1:00pm Supervisor: Dr. Frank Sicheri Contact Ab Atre (studentservices.mogen@utoronto.ca) for Zoom Link Department of Molecular Genetics PhD Oral Seminar

Monday, June 20, 2022 - 2:00pm

Evolutionary persistence of DNA methylation for millions of years Dr. Sandra Catania Department of Biochemistry & Biophysics, University of California, San Francisco Monday, June 20, 2022 - 2:00pm Host: Dr. Liliana Attisano CCBR Red Room Department of Biochemistry Seminar Departmental Search Candidate Poster available: Dr. Sandra Catania.pdf

Thursday, June 23, 2022 - 10:00am

Metabolic Licensing of Beta-Cell Survival in Inflammation Dr. Accalia Fu Dana-Farber Cancer Institute & Harvard Medical School Thursday, June 23, 2022 - 10:00am Host: Dr. Liliana Attisano CCBR Red Room Department of Biochemistry Seminar Departmental Search Candidate

Thursday, June 23, 2022 - 12:00pm

The Promise of Single Cell Omics for understanding disease pathways in the liver Dr. Sonya MacParland Thursday, June 23, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Tuesday, June 28, 2022 - 9:00am

Deciphering the mechanisms of lipid homeostasis in organelles Dr. Arun Peter Department of Biology, University of Fribourg, Switzerland Tuesday, June 28, 2022 - 9:00am Host: Dr. Liliana Attisano CCBR Red Room Department of Biochemistry Seminar Departmental Search Candidate

Tuesday, June 28, 2022 - 10:00am

Modification and Inhibition of the,Pseudomonas aeruginosa Biofilm Exopolysaccharide Pel Erum Razvi Tuesday, June 28, 2022 - 10:00am Supervisor: Dr. P. Lynne Howell; Supervisory committee members: Dr. Roman Melnyk, Dr. Mark Nitz PGCRL Auditorium, 686 Bay St., SickKids PhD Exam Seminar

Thursday, June 30, 2022 - 12:00pm

Uncovering the regulatory role of CFTR in human fetal lung development Dr. Amy Wong, Henry Quach Thursday, June 30, 2022 - 12:00pm Virtual Meeting: Email candice.cumberbatch@sickkids.ca for Teams link Cystic Fibrosis Seminar

Thursday, June 30, 2022 - 4:00pm

Novel Mechanisms of Cell Cycle Regulation Driving Normal Regeneration, Stemness and Cancer Biology Dr. Lisa Porter Professor, Biomedical Sciences, University of Windsor, ON Thursday, June 30, 2022 - 4:00pm Host: Dr. Michael Hoffman PMH, 610 University Avenue, 6th Floor Auditorium, Rm 6-604 OCI Seminar Series Invited Speaker Seminar Poster available: Seminar Notice_Lisa Porter_June 30, 2022.pdf

Wednesday, July 6, 2022 - 9:00am

Charting the genetic architecture of the DNA damage response Michele Olivieri Wednesday, July 6, 2022 - 9:00am Supervisor: Dr. Daniel Durocher Contact Ab Atre (studentservices.mogen@utoronto.ca) for Zoom Link Department of Molecular Genetics PhD Oral Seminar

Wednesday, July 6, 2022 - 2:00pm

Quantitative Fast FLIM-FRET (qF3) to study BCL-2 family protein-protein interactions in live cells Elizabeth Osterlund Wednesday, July 6, 2022 - 2:00pm Supervisor: Dr. David Andrews; Supervisory committee members: Dr. Peter Kim, Dr. Gregory Fairn Zoom PhD Oral Seminar

Wednesday, July 20, 2022 - 9:00am

The landscape of eukaryotic microbiota in the gut microbiome and their impact on bacterial communities and host health Ana Popovic Wednesday, July 20, 2022 - 9:00am Supervisor: Dr. John Parkinson, Supervisory Committee members: Dr. Alex Ensminger, Dr. Leah Cowen Online PhD Oral Seminar

Friday, July 22, 2022 - 10:00am

Phosphoinositide 3-kinase signaling in the nucleolus Dr. Aurélia Lewis, PhD Department of Biological Sciences, University of Bergen, Norway Friday, July 22, 2022 - 10:00am Host: Dr. Julie Brill PGCRL Auditorium, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Invited Speaker Seminar Poster available: Lewis.pdf

Wednesday, July 27, 2022 - 12:30pm

Clustered Protocadherins: A Molecular Barcode for Neuronal Wiring and Survival Samantha Esteves Wednesday, July 27, 2022 - 12:30pm Supervisor: Dr. Julie Lefebvre Contact Ab Atre (studentservices.mogen@utoronto.ca) for Zoom Link Department of Molecular Genetics PhD Oral Seminar

Thursday, August 4, 2022 - 10:00am

Using integrative 'unstructural' biology to characterize the Gram-negative lactoferrin receptor Nicholas Ostan Thursday, August 4, 2022 - 10:00am Supervisor: Dr. Trevor Moraes; Supervisory Committee Members: Dr. James Rini & Dr. Gil Prive Online PhD Oral Seminar

Tuesday, August 9, 2022 - 9:00am

Molecular Basis and Design of B cell Targeting Therapeutics Taylor Sicard Tuesday, August 9, 2022 - 9:00am Supervisor: Dr. Jean-Philippe Julien; Supervisory Committee members: Dr. Roman Melnyk & Dr. James Rini Online seminar PhD Exam Seminar

Tuesday, September 6, 2022 - 4:00pm

Ligand discovery in dark chemical space leading to biological insights John Irwin Ph.D. University of California San Francisco, Department of Pharmaceutical Chemistry Tuesday, September 6, 2022 - 4:00pm Host: Dr. Matthieu Schapira MSB 4171 Pharmacology and Toxicology Seminar Special Seminar Poster available: John Irwin 962022.pdf

Wednesday, September 7, 2022 - 10:00am

Leveraging CRISPR-Cas to Examine the Interplay Between Legionella pneumophila and Mobile Genetic Elements Shayna Deecker Wednesday, September 7, 2022 - 10:00am Supervisor: Dr. Alex Ensminger; Supervisory Comittee members: Dr. Alan Davidson , Dr. William Navarre Online - please contact students supervisor for further details PhD Exam Seminar

Friday, September 9, 2022 - 1:30pm

Single cell wound healing in health and disease Dr. Jesper Nylandsted, PhD Head of Membrane Integrity, Danish Cancer Society Research Center Friday, September 9, 2022 - 1:30pm Host: Dr. John Brumell Via Zoom Program in Cell Biology Seminar Series  Poster available: Nylansted[4].pdf

Monday, September 12, 2022 - 11:00am

Developing a direct neuronal reprogramming strategy to,improve motor function in amyotrophic lateral sclerosisv EunJee Park Monday, September 12, 2022 - 11:00am Supervisor: Dr. Carol Schuurmans (supervisor) & Dr. Isabelle Aubert (supervisory member) , Dr. Lilliana Attisano (supervisory member) Online PhD Exam Seminar

Tuesday, September 20, 2022 - 12:00pm

SickKids Research Institute Faculty Recruitment Seminar: Meghan Azad, PhD & Natalie Rodriguez, MBA, University of Manitoba Meghan Azad, PhD, Natalie Rodriguez, MBA University of Manitoba Tuesday, September 20, 2022 - 12:00pm Host: Jayne Danska, PhD PGCRL Auditorium, 686 Bay St., SickKids Poster available: Faculty recruitment.pdf

Wednesday, September 21, 2022 - 9:00am

Identifying novel vulnerabilities of KRAS using the MaMTH and SIMPL assays Ingrid Grozavu Wednesday, September 21, 2022 - 9:00am Supervisor: Dr. Igor Stagljar; Supervisory Committee members Dr. Michael Ohh & Dr. Vuk Stambolic Online Seminar PhD Exam Seminar

Identifying novel vulnerabilities of KRAS using the MaMTH and SIMPL assays Ingrid Grozavu Wednesday, September 21, 2022 - 9:00am Supervisor: Dr. Igor Stagljar; Supervisory Committee members Dr. Michael Ohh & Dr. Vuk Stambolic Online Seminar PhD Exam Seminar

Thursday, September 22, 2022 - 4:00pm

The tumor microenvironment of lymphoma through a genomic lens Christian Steidl, MD Research Director of the Centre for Lymphoid Cancer, Executive Director Research at BC Cancer, Professor, Department of Pathology and Laboratory Medicine, University of British Columbia Thursday, September 22, 2022 - 4:00pm Host: Robert Kridel, MD Virtual Seminar OCI Seminar Series Invited Speaker Seminar

Friday, September 23, 2022 - 1:00pm

Investigation of a heme uptake system in Acinetobacter baumannii Thomas Bateman Friday, September 23, 2022 - 1:00pm Supervisor: Dr. Trevor Moraes; Supervisory Committee members: Dr. Lynne Howell and Dr. Scott Gray-Owen Online PhD Exam Seminar

Friday, September 23, 2022 - 1:30pm

Organellar alkali cation/proton exchangers and neurodevelopmental disorders Dr. John Orlowski, PhD Department of Physiology, McGill University Friday, September 23, 2022 - 1:30pm Host: Dr. Spencer Freeman PGCRL Rm 1, 2nd Fl, 686 Bay St., SickKids Program in Cell Biology Seminar Series  Poster available: Orlowski.pdf