Modeling breast cancer in mice; testing bioinformatic driven predictions and therapies

Eran Andrechek
Department of Physiology, Michigan State University
Thursday, February 15, 2018 - 3:30pm
CCBR Red Room
Invited Speaker Seminar
Mouse models have long been used to study breast cancer, revealing key insights into the role of various signal transduction pathways. Using a bioinformatics approach to generate testable hypotheses, we have integrated our studies of gene expression and whole genome sequencing with mouse models. Predictions for genes regulating metastasis, tumor suppression and optimal therapy have been tested and will be discussed.
Dr. Sean Egan
Department of Molecular Genetics